DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and AgaP_AGAP004000

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_318459.5	Gene:	AgaP_AGAP004000 / 1278822	VectorBaseID:	AGAP004000	Length:	2647	Species:	Anopheles gambiae

Alignment Length:	222	Identity:	59/222 - (26%)
Similarity:	99/222 - (44%)	Gaps:	22/222 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 LFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELEST 420
            ||||.:.||..     ..:|...:|..:.|||..:...|...||:.|..|...|.:.|..:::..
Mosquito  1933 LFGVPLTALCG-----NSSDGVKIPAQINKLIMMIEMHGLYSEGIYRKSGVSSKIKDLKAKMDRA 1992

  Fly   421 FYQ---NPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTL-PSIDQMNALSI 481
            ...   ....:|  |.:..||.|:::||.:|||:|:||||.:....|.:...| ...|::..|..
Mosquito  1993 VTSADGGGGEMD--FESYNVHVLTNVLKSFLREMPEPLLTFDRYDDFLRAADLSDGSDRVQTLLS 2055

  Fly   482 LCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMF-PPRYIHPSDN-NSIAEQV 544
            |...:||.:......|:....::..|:..|:|:..::|.:.||.:. ..||:...|: |.|..|.
Mosquito  2056 LVKKIPPAHHCLFERLIFHLALVAKLEQYNRMSASSLAIVFAPCVLRTNRYVPAQDSLNDIGRQT 2120

  Fly   545 RMAAQCCRLTNILILRGEKLFQVPNNL 571
            :     |..|.|.    :|:..|.:.|
Mosquito  2121 K-----CMETLIT----QKMLNVKSTL 2138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	59/222 (27%)
AgaP_AGAP004000	XP_318459.5	RA	16..85	CDD:214612
		MYSc	120..779	CDD:214580
		MYSc_Myo9	130..771	CDD:276836
		IQ	836..854	CDD:197470
		C1	1602..1643	CDD:237996
		C1	1843..1891	CDD:237996
		RhoGAP	1934..2127	CDD:295372	54/204 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910