DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and AgaP_AGAP000865

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_316836.5	Gene:	AgaP_AGAP000865 / 1277379	VectorBaseID:	AGAP000865	Length:	1535	Species:	Anopheles gambiae

Alignment Length:	226	Identity:	58/226 - (25%)
Similarity:	106/226 - (46%)	Gaps:	32/226 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 VVLISETDMKRLQTILWLELATI--FDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVT 372
            |:.:|||          |.::||  |...:|:| :|.|    ..:.|.|||..:..:|:|:::.
Mosquito  1302 VLQLSET----------LSISTIIRFVPGEVTL-RRVP----TSKPGALFGAKLQQVIKREKRD- 1350

  Fly   373 GTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATV 437
                  :|..:...:.|:.|||..|.|:.|:.|.......|....|:..|:    .:.|.:...:
Mosquito  1351 ------IPFIVSACVREVERRGMTEVGIYRVSGSASDVAKLKKSFETNAYE----AEQLLKEVDI 1405

  Fly   438 HELSSLLKRWLRELPQPLLTNE----LIQLFYQCHTLPSIDQMNALSILCHLLPPENRNTLRSLL 498
            |.::.:||.:||:||:.|.|::    |...|.:...|....:::.|..:...||..|:.|:..||
Mosquito  1406 HSVTGILKSYLRDLPEALFTDQYYPKLFDAFNRHSNLSEGTRIHELQRIFAELPQPNKATINLLL 1470

  Fly   499 SFFNIIINLKDINKMNVHNVATIMAPSMFPP 529
            .....:...:..|||::||:|.:..|::..|
Mosquito  1471 DHLMRVHQQEIENKMSLHNLAMVFGPTLLRP 1501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	45/178 (25%)
AgaP_AGAP000865	XP_316836.5	RhoGEF	792..981	CDD:279015
		PH_BCR_arthropod	976..1166	CDD:270174
		C2	1208..1317	CDD:301316	7/24 (29%)
		RhoGAP	1336..1531	CDD:295372	44/177 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910