Protein Alignment conu and sh3bp1

DIOPT Version :9

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_031756949.1
• Gene: sh3bp1 / 101733422
• XenbaseID: XB-GENE-984798
• Length: 636
• Species: Xenopus tropicalis
• Alignment Length: 675
• Identity: 133/675 - (19%)
• Similarity: 234/675 - (34%)
• Gaps: 226/675 - (33%)

  Fly    13 QDFSEFLNEYYLQSNSQSIEPEASYEDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDLEPILTTL 77
            ||.::.|.|..|.:: |.:||....  ..:..:.|||.    |..|  .|.:..||..:..|::|
 Frog    21 QDVTDILTEDLLLAD-QQVEPVKKL--AHLVGKRLVSC----LQAP--AGSDREKKLKKLALSSL 76

  Fly    78 SKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDI--------------------RDVFREF----- 117
            |...||.:.:          :.::||.:|..::                    |||.:..
 Frog    77 SWTMAECLKE----------IDSESRMRRTVEMGCCVEGILSQDLADFEISLERDVLQPLAKLSE 131

  Fly   118 DEQGTVTRSRSATPDSLDSLQIDEAWTNNSLPTFVNVYEKN---------TETAIQ---CVEQSN 170
            ::..|:.:.|.    .|..|..|  |  |:..:.::..:||         |.||.:   ..|:.:
 Frog   132 EDLPTILKHRK----QLQKLITD--W--NTAKSRLSQIQKNINAGQGGGSTGTAAKLESLKEEED 188

  Fly   171 EIYLKQNLRRTPSAPPKSGTYADIFRGSQVRCDIPLYSADGVELLG-YSRIGTIQFPRNRSVSDP 234
            |  |::.|.::     |....||::..:....:...|....:||.. |.:         :|:|..
 Frog   189 E--LRRKLEQS-----KDEYIADLYNYTTKEKECERYFIQLLELQAEYHK---------KSLSHL 237

  Fly   235 FCSIGRSKESRSENDARSQKKKSSEVLSASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDT 299
            ..::...|:.:.|....|.::.|:||..         :|:..::..||           ||:
 Frog   238 TDALEELKDLQKETVQDSIEQASAEVYG---------VPLETHLAKFE-----------CEI--- 279

  Fly   300 CDIPSTLFTDVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINAL 364
                                                                      .|.|:|.
 Frog   280 ----------------------------------------------------------AVPISAC 286

  Fly   365 IRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLD 429
            :|.                      ||.:|.:||||.|:.....    :..:|::.......:|.
 Frog   287 VRM----------------------LLAQGMQEEGLFRLAAGAS----VLKKLKACLRAGASDLS 325

  Fly   430 NLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQC-HTLPSIDQMNALSILCHLLPPENRNT 493
            |..  :..|.::..||.:|||||:||:|.||...:..| .|.....::......|..||..|.|.
 Frog   326 NFM--SEPHAVAGALKSYLRELPEPLMTYELFDDWMTCASTKDPEKRLECYRDACKKLPAANYNN 388

  Fly   494 LRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILI 558
            ||.|:.|...:...:::|||...|:|.::.|::...:    ||..:....:..|:..     |::
 Frog   389 LRYLIKFMAKLAEHQEVNKMTPSNIAIVLGPNLLWAK----SDGETSLLDMASASPI-----IVV 444

  Fly   559 LRGEKLFQVPNNLIVESQKTMMGKKGWHRHRNSNEITAKPSG-------KA-------SNVGVGH 609
            ...|.|.....|:..|.....:.:.   .|..|:.:.|:.||       ||       |||....
 Frog   445 SVVEGLLNCAANIFPEDVDFGVSEA---YHETSSVLPAQCSGIKNQEWPKAEETALPPSNVSENT 506

  Fly   610 DST--------VINKYSTNLKHLHP 626
            :|.        .:.|:||: |.|.|
 Frog   507 ESVSESLTEWEELIKFSTS-KALPP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	53/220 (24%)
sh3bp1	XP_031756949.1	BAR	16..250	CDD:416402	53/271 (20%)
		RhoGAP	263..462	CDD:413382	59/316 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910