Protein Alignment conu and arhgap40

DIOPT Version :10

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_073810909.1
• Gene: arhgap40 / 100535133
• ZFINID: ZDB-GENE-121018-2
• Length: 689
• Species: Danio rerio
• Alignment Length: 661
• Identity: 160/661 - (24%)
• Similarity: 273/661 - (41%)
• Gaps: 174/661 - (26%)

  Fly     9 HSDDQDFSEFLNEYYLQSNSQSIEPEAS------YEDGEMEAEWLVSAGYPELTKPFEQGLEVSK 67
            |:.......|..|  :::.....|||:|      .||||.|..||..||.         .|...:
Zfish    95 HAQSLSLESFWTE--VETIRSDCEPESSRRDSRQSEDGEQEELWLQDAGL---------SLVSGE 148

  Fly    68 KDLEP--ILTTLSKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGTVTRSRSAT 130
            :|::.  :.:||:|..|.|:.:.:.:...::|.|.|: |.|  .:||||            .||.
Zfish   149 EDVDKAVLFSTLTKTQAAAVQRRIDSYTCSLRKRNKT-PAR--HVRDVF------------TSAI 198

  Fly   131 PDSLDSLQIDEAWTNNSLPTFVNVYEKNTETAIQCVE-------QSNEIYLKQNLRRTPSAPPKS 188
            ..|.||    |.: |:...|..|: |..|:|....|.       |..||::
Zfish   199 TQSADS----ETY-NSESDTLRNM-ESVTKTQRSAVSGQDTQGLQMEEIFI-------------- 243

  Fly   189 GTYADIFRGSQVRCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQ 253
               .|:           .|......:|                                ..|:..
Zfish   244 ---TDV-----------AYCEQAAIIL--------------------------------KQAKLP 262

  Fly   254 KKKSSEVLSASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDM 318
            :|.||                        |..||..||... :...|.:..|...|   :|:.||
Zfish   263 QKNSS------------------------SSRRDDGSLPRV-ICPQCRLGVTRVQD---LSQQDM 299

  Fly   319 KRLQTILWLELATIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFL 383
            |:::.:..:::..:.|...:.:.:.|..| |:..|..||||.:.:|:..||:  ....:.:||||
Zfish   300 KKVRQLALIDMTALCDLLGLEVKRHKTCK-RKIPESCLFGVPLASLVESDQK--NKPHTQIPLFL 361

  Fly   384 EKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWL 448
            :.|:..|.::|...||:||:.|.:.:.::|..:||::||....:.|.:    :.::.::|||:::
Zfish   362 QTLLSFLEKKGLDSEGILRVPGSQSRIKVLQQQLENSFYSGSFSWDEV----SANDAAALLKKFI 422

  Fly   449 RELPQPLLTNELIQLFYQCHTLPSIDQ-MNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINK 512
            ||||.||||.|.:..|.....:..:.| ::.|::|..|||..|||||::||.|.:.::..:..|:
Zfish   423 RELPAPLLTAEHLNTFSAVRDIADLKQKLHMLNLLVLLLPEPNRNTLKALLEFLSKVVCCERRNR 487

  Fly   513 MNVHNVATIMAPSMFPPRYIHPSDNNSIAEQVRMAAQCCRLTNILILRGEKLFQVPNNLIVESQK 577
            ||:..|:|||||::|..:.: ||...:...:...|.:...:..:||...:.|:.|||.|:  ||.
Zfish   488 MNLWAVSTIMAPNLFLHKAV-PSKLAADGPEKGPAERATDIMRLLIRYQDLLWTVPNFLL--SQV 549

  Fly   578 TMMGKKGWHR---------------HRNSNEITAKPSGKASNVGV--GHDS------TVINKYST 619
            ..:.:....|               |.:|.:...|.:|:...|.:  |..|      ..||..::
Zfish   550 RKLNENSSRRYQFYDKRIKQLLRKIHTDSRDKPDKNAGECRTVKIQLGEVSFSMEFRLSINSRAS 614

  Fly   620 NL-----KHLH 625
            :|     |.||
Zfish   615 DLMSQFHKELH 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	72/220 (33%)
arhgap40	XP_073810909.1	None