DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment conu and arhgap5

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_004917331.1	Gene:	arhgap5 / 100499209	XenbaseID:	XB-GENE-982380	Length:	1500	Species:	Xenopus tropicalis

Alignment Length:	283	Identity:	62/283 - (21%)
Similarity:	112/283 - (39%)	Gaps:	57/283 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 KVSLDKRKPFKR------RRKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGS 395
            ||..||:|...:      ||..|.|.||..::.|:..::.        :|:|::|.:..:...|.
Frog  1230 KVKEDKKKKKTKQLNPPTRRNWESNYFGKPLHELVSPEKP--------IPVFVKKCVEYIEETGL 1286

  Fly   396 REEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNEL 460
            ..|||.|:.|:|...:    .::..|.|: :||:......||:.::..||.:..:||.||:....
Frog  1287 SAEGLYRVSGYKTDQD----NIQKQFDQD-NNLNLASMEVTVNAVAGALKAFFADLPAPLIPYNH 1346

  Fly   461 IQLFYQCHTLP-SIDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVA----- 519
            .....:...:| .::::..|..:....||.|...||.:::..|.:......|.|...|::
Frog  1347 HPDLLEASKIPEKVERLQVLKDILRSFPPVNYEVLRFIIAHLNRVSQHSKTNLMTADNLSICFWP 1411

  Fly   520 TIMAPSMFPPRYIHPSDNN-SIAEQVRMAAQCCRLTNILILRGEKLFQVPNNLIVESQKTMMGKK 583
            |:|.|......:...:.|: |:.|  ....||    ......|:         ||:|...
Frog  1412 TLMRPDFENKEFFSTTKNHQSVIE--TFILQC----QFFFYEGD---------IVDSPSA----- 1456

  Fly   584 GWHRHRNSNEITAKPSGKASNVG 606
                       |:.||.:.|:.|
Frog  1457 -----------TSSPSAQHSSPG 1468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	47/226 (21%)
arhgap5	XP_004917331.1	P-loop_NTPase	28..244	CDD:393306
		RhoGAP-FF1	260..339	CDD:374593
		FF	430..482	CDD:128718
		FF	485..547	CDD:128718
		P-loop_NTPase	<658..736	CDD:393306
		RhoGAP_p190	1256..1440	CDD:239838	42/198 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910