DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and chn2

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_002933428.2	Gene:	chn2 / 100496459	XenbaseID:	XB-GENE-950874	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	55/220 - (25%)
Similarity:	105/220 - (47%)	Gaps:	38/220 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 IRRDQQVTGTD-SSLV-------PLFLEKLIGELLRRGSREEGLLRIGG---HKQKTELLYN--- 415
            ::|.::|...| ::||       |:.::..|.|:..||.:.|||.|:.|   |.:..::.::
Frog   267 LKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDRDG 331

  Fly   416 ---ELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ-M 476
               ::.||.|  ||          ::.::..||.:.|:||.|::|.:....|.:...:.:.|: :
Frog   332 DRADISSTLY--PD----------INIITGALKLYFRDLPIPVITYDTYYKFMEASKISNADERL 384

  Fly   477 NALSILCHLLPPENRNTLRSLLSFF-NIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSI 540
            .|:.....||||.:..|||.|:... .:.:|.|| |.|...|:..:..|::     :.|.:.|::
Frog   385 EAIHEALMLLPPAHYETLRFLMIHLKKVALNEKD-NLMGSENLGIVFGPTL-----MRPPEENAL 443

  Fly   541 AEQVRMAAQCCRLTNILILRGEKLF 565
            |....|..| .::..:||...:.||
Frog   444 ASLNDMRHQ-KQIVQLLIQNEDVLF 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	55/220 (25%)
chn2	XP_002933428.2	SH2_a2chimerin_b2chimerin	52..138	CDD:198215
		C1_betaCHN	209..269	CDD:410407	0/1 (0%)
		RhoGAP_chimaerin	274..467	CDD:239837	51/211 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910