DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and arhgap11a.1

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001121463.1	Gene:	arhgap11a.1 / 100158559	XenbaseID:	XB-GENE-1010876	Length:	946	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	64/234 - (27%)
Similarity:	113/234 - (48%)	Gaps:	28/234 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 GNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELE 418
            |.:||..:::|..:.....|.    ||:.| .::.:.|.:....|||.|..|...:.:||..::
Frog    48 GKVFGTPLHSLPYQYLPEYGN----VPVIL-VIVCKSLEKHLNTEGLFRKSGSVARQKLLKTKI- 106

  Fly   419 STFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQC-HTLPSIDQMNALSIL 482
                   ||.:|...||...:::.:||::.||||:|:|..:|...||:. |.....::::|..:|
Frog   107 -------DNGENCLTTALPCDVAGILKQFFRELPEPVLPTDLQDAFYKAQHLSTDSERISATMLL 164

  Fly   483 CHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNN-----SIAE 542
            ..|:|......|:...||.:.:....|.||||.:|:|.|.||::     :|.:|:.     |..:
Frog   165 TCLIPERTVQILQYFFSFLHAVALRSDANKMNSNNLAVIFAPNL-----LHSNDDGEKISPSTEK 224

  Fly   543 QVRMAAQCCRLTNILILRGEKLFQVPNNLIVESQKTMMG 581
            ::|:.|...|   .||.:...:..|| :.|.|....|:|
Frog   225 KLRVQAAVVR---TLIDQAADIGCVP-DFITEKIPGMLG 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	61/225 (27%)
arhgap11a.1	NP_001121463.1	RhoGAP-ARHGAP11A	50..250	CDD:239859	59/221 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910