DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and arhgap22

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_002940376.2	Gene:	arhgap22 / 100127847	XenbaseID:	XB-GENE-5807514	Length:	544	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	81/285 - (28%)
Similarity:	126/285 - (44%)	Gaps:	45/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 CRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLELATIFDRNKVSLDKRKPFKRR 349
            |||..:|.|.:.:........|..:.....|..::.:..::|                 .||
Frog     6 CRDRKNLSSGDKVTVNHETFLLMANSHHEMEDWVRAIHKVIW-----------------APF--- 50

  Fly   350 RKEEGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLY 414
               .|.:||       :|.:.....::...||.:|:.:..:...|.:||||.|:.|  |.|  |.
Frog    51 ---GGAVFG-------QRLEDAVSLETRHAPLVVEQCVDFIRENGLQEEGLFRLPG--QAT--LV 101

  Fly   415 NELESTFYQNPDNLDNLFRTATVHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ---M 476
            .||:.||  :........::..||.::||||.:|||||:|::.....|.|.:|..:.|.||   .
Frog   102 KELQDTF--DSGGKPTFDKSTDVHTVASLLKLYLRELPEPVIPFSRYQDFLRCAHILSGDQGEGT 164

  Fly   477 NALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRYIHPSDNNSIA 541
            ..||||...|||.|.|.|:.:.||.:.:.:..|.|||||.|:||:.||::..|:...|      .
Frog   165 QELSILIKSLPPVNYNLLKYICSFLDEVQSYSDTNKMNVQNLATVFAPNILRPKQQDP------V 223

  Fly   542 EQVRMAAQCCRLTNILILRGEKLFQ 566
            ..:..|:....|..|||.....:||
Frog   224 ALIEGASLIQHLLTILIHENHWIFQ 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	70/214 (33%)
arhgap22	XP_002940376.2	PH-like	<16..52	CDD:388408	5/58 (9%)
		RhoGAP	53..247	CDD:383032	68/212 (32%)
		Myosin_tail_1	<446..>521	CDD:366712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910