DRSC/TRiP Functional Genomics Resources

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Protein Alignment conu and arhgap35a

DIOPT Version :9

Sequence 1:NP_001036454.1 Gene:conu / 3355133 FlyBaseID:FBgn0039994 Length:629 Species:Drosophila melanogaster
Sequence 2:XP_001343636.1 Gene:arhgap35a / 100004299 ZFINID:ZDB-GENE-120516-2 Length:1536 Species:Danio rerio


Alignment Length:498 Identity:99/498 - (19%)
Similarity:179/498 - (35%) Gaps:148/498 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 VTRSRSATP-----DSLDSLQIDEAWTNNSLPTFVNVYEKNTET--------------AIQCVEQ 168
            |:..|.::|     ||.|.::....:     ||     .:|.:|              :...:.:
Zfish   990 VSSPRCSSPSITLLDSEDDIEPSPPY-----PT-----SRNDDTLTRGGFKLPDLEGDSYSLISE 1044

  Fly   169 SNEIYLKQNLRRTPSAPPKSGTYADI--FRGSQVRCDIPLYSADGVEL-------LGYSRIGTIQ 224
            ...:..|.|.:..|...||.....||  .:.|.:..|:.|:.::...|       .||.      
Zfish  1045 ITNLENKINNKVPPQVRPKPNVTFDIPKTQNSSLYTDLALHGSNRRSLPSVTWPEAGYD------ 1103

  Fly   225 FPRNRSVSDPFCSIGRSKESRSEN------DA---------RSQKKKSSEVLSASENECGRLLPM 274
             |.:  .::|..::.:.:.:..||      |:         .:.|..|:...:.|::|.      
Zfish  1104 -PSD--YAEPMDAVAKPRPTEEENIYSVPHDSTQGKIITIRNANKSHSNGAGNGSDSEA------ 1159

  Fly   275 PYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTD------------VVLISETD---------- 317
                        |||||:....|....:...|:.|            ...|...|          
Zfish  1160 ------------DSSSLERRRKLSALGVKPRLYRDRSKRLGKFSSFRTSFIGSDDELGGTPKAKE 1212

  Fly   318 ----MKRLQTILWLELATIFDRNKV-SLDKRKPFKRRRK---------EEGNLFGVSINALIRRD 368
                .::..|.|..|......||.: ||.:|...|.|.|         .|.|.|||.:..::   
Zfish  1213 DELGAQKGDTSLNEEGEDPKKRNILRSLGRRTTKKTRPKARQTSLSKPPESNYFGVPLANVV--- 1274

  Fly   369 QQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLFR 433
                 |....:|||:||.|..:...|...||:.|:.|:|.:.|    .::..|.|:| |:|.:.:
Zfish  1275 -----TPERPIPLFIEKCIHYIETTGLSTEGIYRVSGNKAEME----SMQRQFDQDP-NIDLVEK 1329

  Fly   434 TATVHELSSLLKRWLRELPQPL----LTNELIQLF------YQCHTLPSIDQMNALSILCHLLPP 488
            ..:|:.::..||.:..|||.||    :..||::.|      ::.||:..:         ....|.
Zfish  1330 DMSVNTVAGALKSFFSELPDPLVPYSMQVELVEAFKINDREHRLHTMKDV---------LRRFPR 1385

  Fly   489 ENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFPPRY 531
            ||.:..:.:::..|.:.....:|.|...|::....|::..|.:
Zfish  1386 ENYDVFKYVITHLNKVSLNSRLNLMTSENLSICFWPTLMRPDF 1428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
conuNP_001036454.1 RhoGAP_ARHGAP18 356..576 CDD:239856 44/186 (24%)
arhgap35aXP_001343636.1 RAB 29..247 CDD:197555
Ras_like_GTPase 29..245 CDD:206648
RhoGAP-FF1 261..340 CDD:293121
FF 431..482 CDD:128718
RhoGAP_p190 1266..1450 CDD:239838 44/185 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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