Protein Alignment conu and arhgap18

DIOPT Version :10

• Sequence 1: NP_001036454.1
• Gene: conu / 3355133
• FlyBaseID: FBgn0039994
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_073790123.1
• Gene: arhgap18 / 100004252
• ZFINID: ZDB-GENE-070502-1
• Length: 701
• Species: Danio rerio
• Alignment Length: 599
• Identity: 156/599 - (26%)
• Similarity: 258/599 - (43%)
• Gaps: 134/599 - (22%)

  Fly    11 DDQDFSEFLNEYYLQSNSQSIEPEASY-----EDGEMEAEWLVSAGYPELTKPFEQGLEVSKKDL 70
            |:|...::..|..:...|...|.:...     ::||.|..||:.||...|   |:|... ..:|.
Zfish   120 DEQAMVDYFKEVEIIQRSGDAETQEELQLKVADEGEQEEAWLMEAGLATL---FDQSAS-DGEDS 180

  Fly    71 EPILTTLSKPHAEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGTVTRSRSATPDSLD 135
            ..:|:||::..|.|:.:.|.||.:|:|.|.|  |...||:|::|:   ...|...|:.
Zfish   181 IALLSTLTRTQAAAVERRVETLKQTLRKRNK--PYAVPDVREIFK---PSTTAAHSKQ------- 233

  Fly   136 SLQIDEAWTNNSLPTFVNVYEKNTETAIQCVEQSNEIYLKQNLRRTPSAPPKSGTYADIFRGSQV 200
                |||                 |:..:...:..|:   :.|..........|       |:..
Zfish   234 ----DEA-----------------ESTERSGSKKQEV---EGLGNGVGLIAAGG-------GADT 267

  Fly   201 RCDIPLYSADGVELLGYSRIGTIQFPRNRSVSDPFCSIGRSKESRSENDARSQKKKSSEVLSASE 265
            ..||.|..:...:.|.|.        ....:|.|.|          :.|.|....|      .|:
Zfish   268 ETDINLEVSFSEQALVYK--------EELKLSKPQC----------QADDRLPDFK------VSQ 308

  Fly   266 NECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWLELA 330
            ::.|:                                     |.|..:|..|||:::.::.:|::
Zfish   309 DKTGQ-------------------------------------TKVGDLSAEDMKKVRRLVLIEMS 336

  Fly   331 TIFDRNKVSLDKRKPFKRRRKEEGNLFGVSINALIRRDQ-QVTGTDSSLVPLFLEKLIGELLRRG 394
            .:||...|.:...|..|.:.:|.| ||||.::.|:.:|| ::.||.   |||.|:.||..:..:|
Zfish   337 ALFDTCGVEVKAHKALKVKVRESG-LFGVPLSVLLDQDQRRIPGTK---VPLILQHLISHIEEQG 397

  Fly   395 SREEGLLRIGGHKQKTELLYNELESTFYQNPDNLDNLF--RTATVHELSSLLKRWLRELPQPLLT 457
            ...||:|||.|...:.:.:.:|||..||      :.||  .:...|:.:||||.::||||.||||
Zfish   398 LDTEGVLRIPGAATRVKAVCHELEHKFY------EGLFPWESLKQHDAASLLKLFIRELPYPLLT 456

  Fly   458 NELIQLFYQCHTLPS-IDQMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATI 521
            .:....|.....||: ..|:.||::|..|||..||:||::|:.||..:|:.||.|||.::|||.:
Zfish   457 VQYFNAFISVLKLPTQKQQLQALNLLVLLLPEHNRDTLKALMEFFQRVIHHKDKNKMTLNNVAVV 521

  Fly   522 MAPSMFPPRYIHPSDNNSIAEQ--VRMAAQCCRLTNILILRGEKLFQVPNNLIVESQK-TMMGKK 583
            |||::|    :.....:.|:||  ..||.....:..:||.....|:.:|..::.:.:| .|..::
Zfish   522 MAPNIF----MCKGFRSKISEQQEFAMATGTANIVRLLIRYQNLLWTIPKFILNQVRKHNMENQR 582

  Fly   584 GWHRHRNSNEITAK 597
            ..:|.|...::..|
Zfish   583 KMNRDRAVKKLLKK 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	81/225 (36%)
arhgap18	XP_073790123.1	None