DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and arhgap15

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001122027.1	Gene:	arhgap15 / 100003547	ZFINID:	ZDB-GENE-070912-314	Length:	465	Species:	Danio rerio

Alignment Length:	356	Identity:	83/356 - (23%)
Similarity:	146/356 - (41%)	Gaps:	78/356 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 DGVELLG---------YSRIGTIQF--PRNRSV---SDPFCSIGRSKESRSENDARSQKKKSSEV 260
            |||:|.|         .||...||.  |.....   :|.|.:|.:..::         .||:.::
Zfish   122 DGVDLNGAVIEWTTEKSSRKNVIQITTPTGHEFLLQADHFPTISKWHDA---------IKKAVDI 177

  Fly   261 LSASE--NECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDI--PSTLFTDVVLISETDMKRL 321
            ||:..  ..|||           .::.|.:|:  .|....||:.  |..        .||..:..
Zfish   178 LSSGSGGQSCGR-----------AALHRSNST--ECLSRPTCESSKPKP--------KETKSEHR 221

  Fly   322 QTILW---LELATIFDRNKVS--LDK---RKPFKRRRKEEG----NLFGVSINALIRRDQQVTGT 374
            ::|::   ...:...|:|.|.  |.|   |:|..:..:|:|    .:||..:..|..|::
Zfish   222 RSIMFKLNYSASDSADKNGVKNRLKKFISRRPSMKTLQEKGIIKDRVFGCHMLTLCDREK----- 281

  Fly   375 DSSLVPLFLEKLIGELLRRGSREEGLLRIGGHK---QKTELLYNELESTFYQNPDNLDNLFRTAT 436
              :.||.|::..:.|:.:||...:|:.|:.|:.   ||...|.::.|..     |..|:.:.  .
Zfish   282 --TTVPKFVKLCVEEVEKRGLEADGIYRVSGNLAIIQKLRFLVDQEEEL-----DLGDSQWE--D 337

  Fly   437 VHELSSLLKRWLRELPQPLLTNELIQLFYQCHTLPSIDQ-MNALSILCHLLPPENRNTLRSLLSF 500
            :|.::..||.:.||||:||.......||.:...:....| :.|:..|.|.||..|.||::.|...
Zfish   338 IHVITGALKMFFRELPEPLFPFRFFDLFVETIKIKEPTQKVQAMKKLIHQLPKPNHNTMKLLFHH 402

  Fly   501 FNIIINLKDINKMNVHNVATIMAPSMFPPRY 531
            ...::.....|.|:...|:.:..|::..|.:
Zfish   403 LRRVLTKSQKNLMSTQGVSIVFGPTLMWPEF 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	45/180 (25%)
arhgap15	NP_001122027.1	PH	67..175	CDD:278594	15/61 (25%)
		PH_ARHGAP9-like	68..176	CDD:270053	15/62 (24%)
		RhoGAP_ARHGAP27_15_12_9	269..453	CDD:239868	45/179 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910