DRSC/TRiP Functional Genomics Resources

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Protein Alignment cta and Gnao1

DIOPT Version :9

Sequence 1:NP_001036421.1 Gene:cta / 3355131 FlyBaseID:FBgn0000384 Length:457 Species:Drosophila melanogaster
Sequence 2:NP_059023.1 Gene:Gnao1 / 50664 RGDID:628732 Length:354 Species:Rattus norvegicus


Alignment Length:360 Identity:153/360 - (42%)
Similarity:204/360 - (56%) Gaps:34/360 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   107 EELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSV 171
            ||.....:||.|:|.|:::..:..:.|||||||||||||||.:|||:|||...|..|.:.:|:.|
  Rat     8 EERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPV 72

  Fly   172 IYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFMEYAPPIS--------R 228
            :|.|.|:.:..::.|.:.|.:.:|...|:.|:    .|.|   ||...||...|.|        |
  Rat    73 VYSNTIQSLAAIVRAMDTLGVEYGDKERKADS----KMVC---DVVSRMEDTEPFSAELLSAMMR 130

  Fly   229 LWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNI 293
            ||.|.||:..|.|.||:|::||..|:||.:.|:...||.||.:|||..|..|.|:.|.....:|:
  Rat   131 LWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNL 195

  Fly   294 PFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNAT 358
            .|...||||||::|:||..||: .||:|||.|:.|.:||||.||..|||:.||..:||:|.||..
  Rat   196 HFRLFDVGGQRSERKKWIHCFE-DVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKF 259

  Fly   359 FKGISIILFLNKTDLLEQK-------VCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRS 416
            |...||||||||.||..:|       :|.||      ||..|    :..|...:|...|.|..||
  Rat   260 FIDTSIILFLNKKDLFGEKIKKSPLTICFPE------YPGSN----TYEDAAAYIQTQFESKNRS 314

  Fly   417 SSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNL 451
            .: ..||.|.|.|.||.||.|||::|.|.|:..||
  Rat   315 PN-KEIYCHMTCATDTNNIQVVFDAVTDIIIANNL 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctaNP_001036421.1 G_alpha 112..455 CDD:214595 151/355 (43%)
G-alpha 133..451 CDD:206639 144/332 (43%)
Gnao1NP_059023.1 G-alpha 34..348 CDD:206639 144/332 (43%)
G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 35..48 12/12 (100%)
G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 174..182 4/7 (57%)
G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 197..206 5/8 (63%)
G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 266..273 6/6 (100%)
G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 324..329 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0082
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54330
OrthoDB 1 1.010 - - D754573at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X53
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.830

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