DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cta and gnai3

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001011471.1	Gene:	gnai3 / 496962	XenbaseID:	XB-GENE-5738634	Length:	354	Species:	Xenopus tropicalis

Alignment Length:	338	Identity:	138/338 - (40%)
Similarity:	209/338 - (61%)	Gaps:	4/338 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQNVIR 178
            :||.||:.|.::.....::|||||||||||||||.:|||:|||...:..|...:|:.|:|.|.|:
Frog    15 RSKMIDRNLREDGEKASKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYKVVVYSNTIQ 79

  Fly   179 GMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFMEYAPPISRLWQDRGIRRAFERRR 243
            .:..::.|..:|.|.:|...|..||....::..::.:.....|.|..|.|||:|.|::..|.|.|
Frog    80 SIIAIIRAMGRLRIDFGDVARADDARQLFVLASSAEEGVMSPELAGVIQRLWEDPGVQACFSRSR 144

  Fly   244 EFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQ 308
            |:|::||.||:|::|:|:|..:|:||.:|:|..|..|.|:.|.....:::.|...||||||::|:
Frog   145 EYQLNDSASYYLNDIERIAQVNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERK 209

  Fly   309 KWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDL 373
            ||..||: .||:|||.|:.|::|.:||||.:.||:.||..:||:|.||..|...||||||||.||
Frog   210 KWIHCFE-GVTAIIFCVALSDYDLLLAEDEEMNRMHESMKLFDSICNNKWFIDTSIILFLNKKDL 273

  Fly   374 LEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHHFTTAIDTRNINVV 438
            .|:|:......|  .||.::|: ::..:...:|...|..:.|......||.|||.|.||:|:..|
Frog   274 FEEKISRSPLTI--CYPEYSGS-NTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFV 335

  Fly   439 FNSVKDTILQRNL 451
            |::|.|.|::.||
Frog   336 FDAVTDVIIKSNL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	138/338 (41%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	131/317 (41%)
gnai3	NP_001011471.1	G-alpha	34..348	CDD:206639	131/317 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930