DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and gna11b

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001007774.1	Gene:	gna11b / 493613	ZFINID:	ZDB-GENE-041121-9	Length:	359	Species:	Danio rerio

Alignment Length:	365	Identity:	161/365 - (44%)
Similarity:	225/365 - (61%)	Gaps:	24/365 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 CCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRII 155
            ||           .:.|..|.:..:.||||.|.::|...||::||||||.||||||||:||||||
Zfish     9 CC-----------LSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRII 62

  Fly   156 HGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFM 220
            ||..:..|....:..::|||:...||.::.|.|.|.|.:   ..||:..:|.|::  .:|:.|.|
Zfish    63 HGAGYTDEDKRGFTKLVYQNIFTSMQAMIRATETLKIGY---KYEQNKANAMLVK--EVDIEKVM 122

  Fly   221 EYAPP----ISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATK 281
            .:..|    :..||.|.||:.|::||||:|:|||..|:|.::.|:|...|:||.:|:|..|..|.
Zfish   123 SFDHPYINAVKMLWSDPGIQEAYDRRREYQLSDSTKYYLSDLDRIAESSYLPTQQDVLRVRIPTT 187

  Fly   282 GVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEES 346
            |:.|:...:|:|.|..|||||||::|:||..||: :||||:|||:.||:||||.|....||:|||
Zfish   188 GIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFE-NVTSIMFLVALSEYDQVLVESDNENRMEES 251

  Fly   347 KNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFM 411
            |.:|.||:....|:..|:||||||.||||:|:  ..:.:..|:|.|:|........:.|||:||:
Zfish   252 KALFRTIITYPWFQNSSVILFLNKKDLLEEKI--SYSHLVDYFPEFDGPQRDAQAAREFILKMFV 314

  Fly   412 SVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNL 451
            .:...|. ..||.|||.|.||.||..||.:|||||||.||
Zfish   315 DLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	157/344 (46%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	147/321 (46%)
gna11b	NP_001007774.1	G_alpha	19..357	CDD:214595	157/344 (46%)
gna11b	NP_001007774.1	G-alpha	40..353	CDD:206639	147/321 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830