DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and gna13a

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001012243.3	Gene:	gna13a / 326825	ZFINID:	ZDB-GENE-030131-5024	Length:	376	Species:	Danio rerio

Alignment Length:	357	Identity:	199/357 - (55%)
Similarity:	258/357 - (72%)	Gaps:	10/357 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 ELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVI 172
            |::|..|||||||.|.:||...::.||:||||||||||||||||||||||.:||.....|:::.|
Zfish    23 EIDQIRKSKEIDKSLSREKTYVKKLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAKEEFRATI 87

  Fly   173 YQNVIRGMQVLLDAREKLNIAWG-----SDGREQDAYDAK--LMECNSLDVPKFMEYAPPISRLW 230
            |.|||:|::||:||||||:|.||     :.|....|:|.:  ||....::...|:.:.|.|..||
Zfish    88 YSNVIKGVRVLVDAREKLHIPWGNPENQAHGETVMAFDTRSSLMAKGMMETKVFLNFLPAIRALW 152

  Fly   231 QDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPF 295
            ||.||:.|::||||||:.:||.||||.:.:|...||:|:.||||..||.|||::|:..:::|:||
Zfish   153 QDSGIQNAYDRRREFQLGESVKYFLDNVDKLGQLDYLPSQKDILLARKPTKGIHEYEFEIKNVPF 217

  Fly   296 VFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFK 360
            ..|||||||::|::|..||| |||||:|||||||:||||.|||:||||.||.|||:|||||..|.
Zfish   218 KMVDVGGQRSERKRWFECFD-SVTSILFLVSSSEYDQVLMEDRQTNRLTESLNIFETIVNNRVFA 281

  Fly   361 GISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHH 425
            .:|||||||||||||.||  ...:|:.|:..|.|.||::.|||.|:::.|.:.||......:|||
Zfish   282 NVSIILFLNKTDLLEDKV--KTVNIKDYFSEFTGEPHNLQDVQKFLVECFRNKRREQQQKPLYHH 344

  Fly   426 FTTAIDTRNINVVFNSVKDTILQRNLNALMLQ 457
            |||||:|.||.:||..||||||..||..||||
Zfish   345 FTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	193/349 (55%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	181/324 (56%)
gna13a	NP_001012243.3	G_alpha	27..374	CDD:214595	193/349 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586260
Domainoid	1	1.000	373	1.000	Domainoid score	I842
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55976
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1970
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D299429at33208
OrthoFinder	1	1.000	-	-		FOG0003447
OrthoInspector	1	1.000	-	-		otm25591
orthoMCL	1	0.900	-	-		OOG6_106101
Panther	1	1.100	-	-	O	PTHR10218
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.810