DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and GNAL

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_892023.1	Gene:	GNAL / 2774	HGNCID:	4388	Length:	458	Species:	Homo sapiens

Alignment Length:	380	Identity:	130/380 - (34%)
Similarity:	194/380 - (51%)	Gaps:	67/380 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 EQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQ 174
            |.|..|:.||:.|..:|...::..:|||||||||||||.:|||||:|...|:.|
Human    97 EARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPE----------- 150

  Fly   175 NVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKF-------------------- 219
               ...|.:||.|:.:          :||. ..::...|..:|..
Human   151 ---EKKQKILDIRKNV----------KDAI-VTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPI 201

  Fly   220 ------MEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRK 278
                  .|:...:.:||.|.|::..|||..|:|:.|...|||:.|..::..||.||.:|:|.||.
Human   202 TDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRV 266

  Fly   279 ATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRL 343
            .|.|::|...:|..:.|...||||||.:|:||.:|| :.||:||::.:.|.::.|:.||..||||
Human   267 LTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCF-NDVTAIIYVAACSSYNMVIREDNNTNRL 330

  Fly   344 EESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHF------------NGNP 396
            .||.::|::|.||...:.|||||||||.|:|.:||...::.|..|:|.:            .|..
Human   331 RESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED 395

  Fly   397 HSVLDVQNFILQMFMSVRRSSSISR--IYHHFTTAIDTRNINVVFNSVKDTILQR 449
            ..|...:.||..:|:.:..::...:  .|.|||.|:||.||..|||..:| |:||
Human   396 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD-IIQR 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	129/378 (34%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	123/357 (34%)
GNAL	NP_892023.1	G_alpha	99..455	CDD:214595	129/378 (34%)
GNAL	NP_892023.1	G-alpha	120..452	CDD:206639	123/357 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820