DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and Gnaz

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_037321.1	Gene:	Gnaz / 25740	RGDID:	2717	Length:	355	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	141/365 - (38%)
Similarity:	202/365 - (55%)	Gaps:	25/365 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 RSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLE 167
            |.:.||.|...:|:.||:.|..|....||::||||||...|||||.:|||:|||...|:.|...|
  Rat     4 RQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKE 68

  Fly   168 YQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFMEYAPPI----SR 228
            |:.:|..|.|..:..::.|...|.|.:.:..|   ||||..:...:.......|..|.:    .|
  Rat    69 YKPLIIYNAIDSLTRIIRALAALKIDFHNPDR---AYDAVQLFALTGPAESKGEITPELLGVMRR 130

  Fly   229 LWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNI 293
            ||.|.|.:..|.|..|:.:.|:.:|:|::::|:|.|||:||.:|||..|..|.|:.|.....:.:
  Rat   131 LWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKEL 195

  Fly   294 PFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNAT 358
            .|..|||||||::|:||..||: .||:|||.|..|.:|..|.||.:|:|:.||..:||:|.||..
  Rat   196 TFKMVDVGGQRSERKKWIHCFE-GVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNW 259

  Fly   359 FKGISIILFLNKTDLLEQK-------VCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRS 416
            |...|:||||||.|||.:|       ||         :|.:.|. ::..:...:|.:.|..:.|:
  Rat   260 FINTSLILFLNKKDLLSEKIRRIPLSVC---------FPEYKGQ-NTYEEAAVYIQRQFEDLNRN 314

  Fly   417 SSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALML 456
            .....||.|||.|.||.||..||::|.|.|:|.||..:.|
  Rat   315 KETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	136/353 (39%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	127/328 (39%)
Gnaz	NP_037321.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		8/21 (38%)
		G-alpha	34..349	CDD:206639	127/328 (39%)
		G1 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	35..48		9/12 (75%)
		G2 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	174..182		4/7 (57%)
		G3 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	197..206		6/8 (75%)
		G4 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	325..330		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830