DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cta and gpa2

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_593803.1	Gene:	gpa2 / 2541720	PomBaseID:	SPAC23H3.13c	Length:	354	Species:	Schizosaccharomyces pombe

Alignment Length:	357	Identity:	122/357 - (34%)
Similarity:	195/357 - (54%)	Gaps:	29/357 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 EELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSV 171
            |..|.:..:.:|:|.:|......::..|:|||||.:|||||..||::|::...|..|.::.:..|
pombe     9 ESGESKKLNSKIEKQIENASKKDKKIYKVLLLGASDSGKSTISKQIKILNKNGFSQEEIMTFIPV 73

  Fly   172 IYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKF---------MEYAPPIS 227
            |.:|::...:.|:    |:.:..|.:......::.:::|       ||         ......|:
pombe    74 IRRNLLESAKTLV----KIIVQKGINLDPLGTHNCEIIE-------KFNPTPGELINANIGQAIT 127

  Fly   228 RLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQN 292
            .||....: |:.....:..:.||..||......:.:..||||..|||..|.:|.|:.|....:.:
pombe   128 SLWSANSV-RSCTYGNDSVLIDSAPYFFSRADEICSRHYVPTIDDILRSRNSTLGISEISFTLDH 191

  Fly   293 IPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDR--KTNRLEESKNIFDTIVN 355
            :.....|||||||:|:||..||: :|.||||.||.:::|:.|.|..  :.|||.||.::||:|:|
pombe   192 LQIRMFDVGGQRTERRKWIYCFE-NVNSIIFCVSLNDYDKKLYERAAPERNRLVESISLFDSIIN 255

  Fly   356 NATFKGISIILFLNKTDLLEQKVCN-PETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSI 419
            :..|...||||||||.||..:|:.: |..|   |:|.:.|. :||..:..:||.:|::...:.:.
pombe   256 SQWFMHSSIILFLNKFDLFRKKLEHVPFQD---YFPQYEGK-NSVKSITRYILWLFVNPSINRAK 316

  Fly   420 SRIYHHFTTAIDTRNINVVFNSVKDTILQRNL 451
            ..||.|.|||:||.||.|||::||:||||.:|
pombe   317 HNIYPHITTAVDTSNIKVVFSAVKETILQHSL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	120/352 (34%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	116/329 (35%)
gpa2	NP_593803.1	G_alpha	14..352	CDD:214595	120/352 (34%)
gpa2	NP_593803.1	G-alpha	35..348	CDD:206639	116/329 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10218
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
TreeFam	0	0.000	Not matched by this tool.
	4	4.010