DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and Gnas

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_038960221.1	Gene:	Gnas / 24896	RGDID:	2716	Length:	1145	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	146/394 - (37%)
Similarity:	210/394 - (53%)	Gaps:	54/394 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 RLRSTPEELEQR-------YKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGV 158
            |.:...|.:|.|       .:||.|||.||:||..:....:|||||||||||||.:|||||:|..
  Rat   752 RKQMRKEAMEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVN 816

  Fly   159 NFD-----------------YELLLEYQSV------IYQNVIRGMQVLLDAREKLNIAWGSDGRE 200
            .|:                 .|...:.|.:      ..:.::..|..|:...|..|    .:.:.
  Rat   817 GFNGEGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELAN----PENQF 877

  Fly   201 QDAYDAKLMECNSLDV-PKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATP 264
            :..|...:|...:.|. |:|.|:|   ..||:|.|:|..:||..|:|:.|...||||:|..:...
  Rat   878 RVDYILSVMNVPNFDFPPEFYEHA---KALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQA 939

  Fly   265 DYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSE 329
            ||||:.:|:|.||..|.|::|...:|..:.|...||||||.:|:||.:|| :.||:|||:|:||.
  Rat   940 DYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCF-NDVTAIIFVVASSS 1003

  Fly   330 FDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHF-- 392
            ::.|:.||.:||||:|:.|:|.:|.||...:.||:||||||.|||.:||...::.|..|:|.|
  Rat  1004 YNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFAR 1068

  Fly   393 ----------NGNPHSVLDVQNFILQMFMSVRRSSSISR--IYHHFTTAIDTRNINVVFNSVKDT 445
                      .|....|...:.||...|:.:..:|...|  .|.|||.|:||.||..|||..:|
  Rat  1069 YTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRD- 1132

  Fly   446 ILQR 449
            |:||
  Rat  1133 IIQR 1136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	143/383 (37%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	133/355 (37%)
Gnas	XP_038960221.1	PHA03247	<122..560	CDD:223021
		UDM1_RNF168_RNF169-like	741..>783	CDD:409016	11/30 (37%)
		G-alpha	791..1139	CDD:206639	133/355 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010