DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and gpa-12

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_509557.1	Gene:	gpa-12 / 181157	WormBaseID:	WBGene00001674	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	177/351 - (50%)
Similarity:	243/351 - (69%)	Gaps:	13/351 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGV-NFDYELLLEYQSVIYQNVI 177
            ::|.|:|.|.||:...|||:.|||||:||||||||:|||.||||. .|..:.:..|:..||||.|
Worm    11 RTKTIEKELHKERKIMRRQINLLLLGSGESGKSTFVKQMHIIHGAGEFTADEVRAYRQQIYQNAI 75

  Fly   178 RGMQVLLDAREKLNIAWGSDGREQDAYDAKLME------CNSLDVPKFMEYAPPISRLWQDRGIR 236
            ..|:||||||.||.|||....|:.:.  .|:|.      ...:|...|:|.||.||..|.|..||
Worm    76 SAMRVLLDARNKLGIAWEDPKRQVEV--EKVMRFSVGDLLKGIDFTTFVEVAPIISDFWNDAAIR 138

  Fly   237 RAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVG 301
            :.:|:|..||||||..||.:.|.|:|.||:.||::|||.|||||:|:.|...::..|||.|:|||
Worm   139 KTYEQRNLFQISDSCQYFFEHIPRIAMPDFYPTNRDILFCRKATRGISEHIFEINKIPFRFIDVG 203

  Fly   302 GQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIIL 366
            |||:|||||.:|| :.:|||:|:|:|:|:|||:.|||:|||:.||:::|:|||||..|..:||||
Worm   204 GQRSQRQKWFQCF-TDITSILFMVASNEYDQVILEDRRTNRVVESRSVFETIVNNRAFSNVSIIL 267

  Fly   367 FLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHHFTTAID 431
            |:||.|||::||  |::|||.|:..|.|:...|.|||.|::..|.:.||..: ...::|||||:|
Worm   268 FMNKNDLLQEKV--PKSDIRQYFTDFTGDHTLVRDVQFFLVDKFEASRRDRA-RPFFYHFTTAVD 329

  Fly   432 TRNINVVFNSVKDTILQRNLNALMLQ 457
            |.||..||..|:::||::||..||:|
Worm   330 TENIRRVFRDVRESILEQNLKTLMMQ 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	174/347 (50%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	163/324 (50%)
gpa-12	NP_509557.1	G_alpha	10..353	CDD:214595	174/347 (50%)
gpa-12	NP_509557.1	G-alpha	30..349	CDD:206639	163/324 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157369
Domainoid	1	1.000	329	1.000	Domainoid score	I626
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1388
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D299429at33208
OrthoFinder	1	1.000	-	-		FOG0003447
OrthoInspector	1	1.000	-	-		oto19317
orthoMCL	1	0.900	-	-		OOG6_106101
Panther	1	1.100	-	-	LDO	PTHR10218
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4590
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800