DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and gpa-4

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_499921.2	Gene:	gpa-4 / 176865	WormBaseID:	WBGene00001666	Length:	359	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	139/376 - (36%)
Similarity:	218/376 - (57%)	Gaps:	37/376 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CFRCCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQM 152
            ||...|:               |.:.:||.||:.|..:......::||||||||||||||.::||
Worm     3 CFHSTGS---------------EAKKRSKLIDEQLRHDHERCVGEIKLLLLGAGESGKSTIVRQM 52

  Fly   153 RIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDA----------YDAK 207
            ||:|...|:.:..:.|:.|::.|:::.|..:|.|.:.|||::....||:||          .:|:
Worm    53 RILHETGFNKQEQMAYRPVVFSNMVQSMLAILKAMQPLNISFTDAAREEDARMFISHFLHVNNAE 117

  Fly   208 LMECNSLDVPKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKD 272
            |.|..||::...|:      :||.|.|:::..:|..|:|::||..|:.:.:.|:::..|:||..|
Worm   118 LSEAFSLELSDLMK------QLWMDEGVKKCVKRAHEYQLNDSAEYYFNALDRISSSSYLPTQDD 176

  Fly   273 ILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAED 337
            ||..|..:.|:.|.....:::.|...||||||::|:||..||| |||::||.|:.||:|..||||
Worm   177 ILRARVKSTGIVETTFMYKDLCFKMFDVGGQRSERKKWIHCFD-SVTAVIFCVALSEYDLRLAED 240

  Fly   338 RKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDV 402
            :..||:.||..:||:||||..|...||||||||.|:.|:::  ..|.:...:|.:.|. .::.:.
Worm   241 QTMNRMHESMQLFDSIVNNCWFTETSIILFLNKMDIFEERI--RYTPLTVCFPEYQGG-MTITET 302

  Fly   403 QNFILQMF--MSVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNL 451
            ..||...|  ::.|::.:...||.|||.|.||.||..||::|.|.|::.||
Worm   303 STFIQSRFEILNKRQTPAQKEIYSHFTCATDTNNIRFVFDAVTDIIIRNNL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	135/352 (38%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	128/329 (39%)
gpa-4	NP_499921.2	G_alpha	12..357	CDD:214595	135/352 (38%)
gpa-4	NP_499921.2	G-alpha	33..353	CDD:206639	128/329 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830