Protein Alignment cta and Gnat1

DIOPT Version :10

• Sequence 1: NP_001036421.1
• Gene: cta / 3355131
• FlyBaseID: FBgn0000384
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_032166.1
• Gene: Gnat1 / 14685
• MGIID: 95778
• Length: 350
• Species: Mus musculus
• Alignment Length: 346
• Identity: 139/346 - (40%)
• Similarity: 216/346 - (62%)
• Gaps: 13/346 - (3%)

  Fly   110 EQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQ 174
            |::: |:|::|.|:::.....|.|||||||||||||||.:|||:|||...:..|..||:.::||.
Mouse     8 EEKH-SRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYG 71

  Fly   175 NVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLME-CNSLD---VPKFMEYAPPISRLWQDRGI 235
            |.::.:..::.|...|||.:|...|:.||  .|||. .::::   :||  |.:..|.|||:|.||
Mouse    72 NTLQSILAIVRAMTTLNIQYGDSARQDDA--RKLMHMADTIEEGTMPK--EMSDIIQRLWKDSGI 132

  Fly   236 RRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDV 300
            :..|:|..|:|::||..|:|.:::||.||.||||.:|:|..|..|.|:.|.....:::.|...||
Mouse   133 QACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDV 197

  Fly   301 GGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNATFKGISII 365
            ||||::|:||..||: .||.|||:.:.|.:|.||.||.:.||:.||.::|::|.|:..|...||:
Mouse   198 GGQRSERKKWIHCFE-GVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIV 261

  Fly   366 LFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIYHHFTTAI 430
            |||||.|:..:|:......|  .:|.::| |::..|..|:|...|:.:.....:..||.|.|.|.
Mouse   262 LFLNKKDVFSEKIKKAHLSI--CFPDYDG-PNTYEDAGNYIKVQFLELNMRRDVKEIYSHMTCAT 323

  Fly   431 DTRNINVVFNSVKDTILQRNL 451
            ||:|:..||::|.|.|::.||
Mouse   324 DTQNVKFVFDAVTDIIIKENL 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	138/344 (40%)
Gnat1	NP_032166.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		5/13 (38%)
		G-alpha	30..344	CDD:206639	131/321 (41%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	31..44		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	169..177		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	192..201		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	261..268		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	320..325		2/4 (50%)
		Interaction with RHO. /evidence=ECO:0000250|UniProtKB:P04695	340..350		2/5 (40%)