Protein Alignment cta and Gnas

DIOPT Version :9

• Sequence 1: NP_001036421.1
• Gene: cta / 3355131
• FlyBaseID: FBgn0000384
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_034439.2
• Gene: Gnas / 14683
• MGIID: 95777
• Length: 1133
• Species: Mus musculus
• Alignment Length: 393
• Identity: 147/393 - (37%)
• Similarity: 210/393 - (53%)
• Gaps: 53/393 - (13%)

  Fly   101 RLRSTPEELEQR-------YKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIH-- 156
            |.:...|.:|.|       .:||.|||.||:||..:....:|||||||||||||.:|||||:|
Mouse   741 RKQMRKEAIEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGESGKSTIVKQMRILHVN 805

  Fly   157 --------------GVNFDYELLLEYQSV------IYQNVIRGMQVLLDAREKLNIAWGSDGREQ 201
                          ..|.|.|...:.|.:      ..:.::..|..|:...|..|    .:.:.:
Mouse   806 GFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELAN----PENQFR 866

  Fly   202 DAYDAKLMECNSLDV-PKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPD 265
            ..|...:|...:.|. |:|.|:|   ..||:|.|:|..:||..|:|:.|...||||:|..:...|
Mouse   867 VDYILSVMNVPNFDFPPEFYEHA---KALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQAD 928

  Fly   266 YVPTHKDILHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEF 330
            |||:.:|:|.||..|.|::|...:|..:.|...||||||.:|:||.:|| :.||:|||:|:||.:
Mouse   929 YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCF-NDVTAIIFVVASSSY 992

  Fly   331 DQVLAEDRKTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHF--- 392
            :.|:.||.:||||:|:.|:|.:|.||...:.||:||||||.|||.:||...::.|..|:|.|
Mouse   993 NMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARY 1057

  Fly   393 ---------NGNPHSVLDVQNFILQMFMSVRRSSSISR--IYHHFTTAIDTRNINVVFNSVKDTI 446
                     .|....|...:.||...|:.:..:|...|  .|.|||.|:||.||..|||..:| |
Mouse  1058 TTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRD-I 1121

  Fly   447 LQR 449
            :||
Mouse  1122 IQR 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	144/382 (38%)
		G-alpha	133..451	CDD:206639	134/354 (38%)
Gnas	NP_034439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..195
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..552
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..648
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	724..744		1/2 (50%)
		G_alpha	759..1130	CDD:214595	143/375 (38%)
		G-alpha	780..1127	CDD:206639	134/354 (38%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	781..794		11/12 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	807..828		3/20 (15%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	935..943		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	958..967		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	1027..1034		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	1103..1108		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850