DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and Gna14

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_032163.3	Gene:	Gna14 / 14675	MGIID:	95769	Length:	355	Species:	Mus musculus

Alignment Length:	366	Identity:	157/366 - (42%)
Similarity:	224/366 - (61%)	Gaps:	16/366 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 CCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRII 155
            ||           .:.||.|.:..|.||::.|.::|...||::||||||.||||||||:||||||
Mouse     5 CC-----------LSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRII 58

  Fly   156 HGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFM 220
            ||..:..|....:..::|||:...||.::.|.:.|.|.:..:..:::|...:.:|.:.:.... .
Mouse    59 HGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALS-R 122

  Fly   221 EYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYE 285
            :....|.:||.|.||:..::||||:|:|||..|:|.:|:|:|.|.:|||.:|:|..|..|.|:.|
Mouse   123 DQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIE 187

  Fly   286 FCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIF 350
            :...::||.|..|||||||::|:||..||: |||||||||:.||:||||||....||:||||.:|
Mouse   188 YPFDLENIIFRMVDVGGQRSERRKWIHCFE-SVTSIIFLVALSEYDQVLAECDNENRMEESKALF 251

  Fly   351 DTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRR 415
            .||:....|...|:||||||.||||:|:.  .:.:..|:|.:.|....|...::|||:::.. :.
Mouse   252 RTIITYPWFLNSSVILFLNKKDLLEEKIM--YSHLISYFPEYTGPKQDVKAARDFILKLYQD-QN 313

  Fly   416 SSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALML 456
            ......||.|||.|.||.||..||.:|||||||.||....|
Mouse   314 PDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	151/342 (44%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	142/317 (45%)
Gna14	NP_032163.3	G_alpha	16..353	CDD:214595	151/341 (44%)
		G-alpha	36..349	CDD:206639	142/317 (45%)
		G1 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	37..50		11/12 (92%)
		G2 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	174..182		3/7 (43%)
		G3 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	197..206		6/8 (75%)
		G4 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01230	325..330		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841835
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.760