Protein Alignment cta and GNA13

DIOPT Version :10

• Sequence 1: NP_001036421.1
• Gene: cta / 3355131
• FlyBaseID: FBgn0000384
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_006563.2
• Gene: GNA13 / 10672
• HGNCID: 4381
• Length: 377
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 204/379 - (53%)
• Similarity: 262/379 - (69%)
• Gaps: 24/379 - (6%)

  Fly    88 CFRCCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQM 152
            ||..|          ..|..|.||:.|||||||.|.:||...:|.||:|||||||||||||||||
Human    14 CFPGC----------LLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQM 68

  Fly   153 RIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNS---- 213
            |||||.:||.....|::..||.|||:||:||:||||||:|.||.:..:|  :..|:|..::
Human    69 RIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQ--HGDKMMSFDTRAPM 131

  Fly   214 -----LDVPKFMEYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDI 273
                 ::...|::|.|.|..||.|.||:.|::||||||:.:||.||||.:.:|..|||:|:.:||
Human   132 AAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196

  Fly   274 LHCRKATKGVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDR 338
            |..|:.|||::|:..:::|:||..|||||||::|::|..||| |||||:||||||||||||.|||
Human   197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFD-SVTSILFLVSSSEFDQVLMEDR 260

  Fly   339 KTNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQ 403
            .||||.||.|||:|||||..|..:|||||||||||||:||  ....|:.|:..|.|:||.:.|||
Human   261 LTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKV--QIVSIKDYFLEFEGDPHCLRDVQ 323

  Fly   404 NFILQMFMSVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALMLQ 457
            .|:::.|.:.||......:||||||||:|.||.:||..||||||..||..||||
Human   324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	193/351 (55%)
GNA13	NP_006563.2	G_alpha	29..375	CDD:214595	193/350 (55%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		4/4 (100%)