DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cta and gnat2

DIOPT Version :9

Sequence 1:	NP_001036421.1	Gene:	cta / 3355131	FlyBaseID:	FBgn0000384	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001135577.1	Gene:	gnat2 / 100216126	XenbaseID:	XB-GENE-6258657	Length:	354	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	131/353 - (37%)
Similarity:	215/353 - (60%)	Gaps:	14/353 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 STPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEY 168
            ::.|:.|...:|||::|.|:::.....:.|||||||||||||||.:|||:|||...:..:..:|:
Frog     5 ASAEDKELAKRSKELEKKLQEDAAMDAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSEQECIEF 69

  Fly   169 QSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLME--CNSLD---VPKFMEYAPPISR 228
            :::||.|:::.:..::.|...|.|.:|...|   |.|.:::.  .:|::   :|:  |....|.:
Frog    70 RAIIYGNILQSILAIIRAMSTLGIDYGDSSR---ADDGRILSHLADSIEEGTMPQ--ELVDVIKK 129

  Fly   229 LWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKVQNI 293
            ||:|.|::..|||..|:|::||.:|:|:::.|:...:|:|..:|:|..|..|.|:.|.....:::
Frog   130 LWKDDGVQACFERAAEYQLNDSAAYYLNQLDRITASNYIPNEQDVLRSRVKTTGIIESQFSFKDL 194

  Fly   294 PFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEESKNIFDTIVNNAT 358
            .|...||||||::|:||..||: .||.|||..:.|.:|.||.||.:.||:.||.::|::|.|:..
Frog   195 HFRMFDVGGQRSERKKWIHCFE-GVTCIIFCGALSAYDMVLVEDEEVNRMHESLHLFNSICNHKF 258

  Fly   359 FKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFMSVRRSSSISRIY 423
            |...||:|||||.||.|||:......|  .:|.::| |::..|..|:|.|.|:.:........||
Frog   259 FAATSIVLFLNKKDLFEQKIKKVHLSI--CFPDYDG-PNTFDDAGNYIKQQFLDLNMRKDSKEIY 320

  Fly   424 HHFTTAIDTRNINVVFNSVKDTILQRNL 451
            .|.|.|.||:|:..||::|.|.|::..|
Frog   321 GHMTCATDTQNVKFVFDAVTDIIIKETL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	129/345 (37%)
cta	NP_001036421.1	G-alpha	133..451	CDD:206639	123/322 (38%)
gnat2	NP_001135577.1	G-alpha	34..348	CDD:206639	123/322 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930