Protein Alignment lt and VPS41

DIOPT Version :10

• Sequence 1: NP_001036415.2
• Gene: lt / 3355130
• FlyBaseID: FBgn0002566
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_172297.2
• Gene: VPS41 / 837340
• AraportID: AT1G08190
• Length: 980
• Species: Arabidopsis thaliana
• Alignment Length: 927
• Identity: 281/927 - (30%)
• Similarity: 436/927 - (47%)
• Gaps: 135/927 - (14%)

  Fly    18 NEEDVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNLSASER 82
            :|.:.||:.||.|:..::..:|:.|..:|.||..:.:..||..|.|.|.|..||.|      .|.
plant    36 DEAEEEPRLKYQRMGGNVPALLSNDAASCIAVAARMIALGTHDGTVRILDLLGNQV------KEF 94

  Fly    83 HTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEPD-SKAHIKRF 146
            ..|...||:|:.|.:|||:.:|||||.|.|..||:.|......:.:.:|.:||:|| :|...|||
plant    95 RAHTAPVNDINFDTEGEYIGSCSDDGSVVINSLFTDDEKMKFDYHRPMKAISLDPDYTKKQSKRF 159

  Fly   147 VVGDDKLILYERNLLKKL---KPVELCSVEGSVLSICWHGNFIAWASHIGVRVYDLNERCSLGLI 208
            |.|.....||..:  ||.   |...|.|.||.:.|:.|.|:.||||:.:||:|||..:...:..|
plant   160 VAGGLAGHLYMNS--KKWFGNKDQVLHSGEGPIHSVKWRGSLIAWANDVGVKVYDTAKDQRVTFI 222

  Fly   209 KWEVP-PQERLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRNSIEASTGNL------PVYIVDP 266
              |.| ...|.|....||.|.:...|:|||..::::..|:   |.:..||..      .:..||.
plant   223 --EKPRGSPRPEALLPHLVWQDDTLLVIGWGTSVKIASIK---SDQQQTGTFRQIQMSSLTQVDI 282

  Fly   267 ISTFQTTFYVCGLAPLSAKQLVVLGF-------RKEKSSCF------KALRPVLCVIEYKMNNSE 318
            :::|||::|:.|:||. ...||:|.:       .||.||..      .|.||.:.::.:   |::
plant   283 VASFQTSYYISGIAPF-GDSLVILAYIPIEGDGEKEFSSTTTLSRQGNAQRPEIRIVSW---NND 343

  Fly   319 EICTDSLTLRGFEEYTVNDYSL-----------GG---IIEENRFYIVAPKDIVVASLIETDDRI 369
            |:..|:|.:.|||.|...||||           ||   ..:|..:|||:|||:|:|...:.:|.|
plant   344 ELTMDALPVHGFEHYKAKDYSLAHAPFPGSSYAGGQWAAGDEPLYYIVSPKDVVIAKPRDAEDHI 408

  Fly   370 EWLIKHSKFEEAMELISANGGNVPVL-SVAKLYINHLLALKKYDDAAKLCLRMLGNDKVLWEEEV 433
            .||::|...|:|:..:.|:.|...:: .|...|::||:..:||.:||.||.::|......||..|
plant   409 NWLLQHGFHEKALAAVEASEGRTELIDKVGAGYLDHLIVERKYAEAASLCPKLLRGSASAWERWV 473

  Fly   434 FKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLY------EFLKFDVCGFLNLIKEWPSHLYDGL 492
            |.|.:.:||..:..|:|| |..:|...|||:.|.      .:.|    ..|:.:|.||..:|..|
plant   474 FHFAQLRQLPVLVPYMPT-DNPRLKDTVYEVALVALATNPSYHK----ELLSAVKSWPRSVYSAL 533

  Fly   493 AVINAIHDNFR-KHYANQLLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRYELYDVISKLI 556
            .||:||..... ....:.|.|:||.||...|.::.|..:|..|...:||..|.:|.|::.|...:
plant   534 TVISAIEPQLNTSSMTDALKEALAELYVIDGQYQKAFSLYADLLKPEVFDFIEKYSLHEAIRGKV 598

  Fly   557 IPLIQLDRDCAFEILLDKKKI--KTEIVVHQLE--------------HNQEYLYWYLDSL--LKK 603
            :.|:.||...|..:.:..:.:  .:|:|...|:              .::.|||.||.:|  :..
plant   599 VQLMLLDCKRATVLFIQNRDLIPPSEVVPQLLKAGKNPQVLKAGKKCDSRYYLYLYLHALFEVSH 663

  Fly   604 DPSNVFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQENFYPEIVYLLGCMGGVEASEA 668
            |....|....:.|||.:|...|||||:.|:.|.:::|..:|.:::|..|.|::||.||  .|.:|
plant   664 DTGKDFHDMQVELYAEYDTKMLLPFLRSSQHYKLEKAYELCVKKDFLREQVFVLGRMG--NAKQA 726

  Fly   669 LNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPAVVVGKIKMGQ 733
            |.:||:::.|||.|:||.....|.|||..||.:....||:|..:|:..|....|..:|..:..|.
plant   727 LAVIINKLGDIEEAVEFVSMQHDDDLWEELIKQCLNKPEMVGLLLEHTVGNLDPLYIVNMVPNGL 791

  Fly   734 NIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQVSYEQ---------- 788
            .||.||..|:|::..|..:..:......|...|...:..:.....|||..:|:|.
plant   792 EIPRLRDRLVKIVTDYRTETSLRHGCNDILKTDIVNLLVKCFNEARRGVCLSHEDDDSRAKREDN 856

  Fly   789 ------------------------------LCSLCHRPVLMAGTHLYCIIRLECGHVYHKPCIQG 823
                                          .|.:|..||.:.|.   .::...|.|.||:.|:..
plant   857 NRSSFSQRMVVDKSLSIKMTEVKSKTRGDTRCCMCFDPVSIRGD---TVVVFFCCHAYHETCLMD 918

  Fly   824 ELLKNCNECNLWKLTVG 840
            ....|.|.    |.|.|
plant   919 AAFSNNNH----KTTKG 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lt	NP_001036415.2	WD40 repeat	33..81	CDD:293791	14/47 (30%)
		WD40 repeat	90..123	CDD:293791	16/32 (50%)
		WD40 repeat	130..168	CDD:293791	16/41 (39%)
		CLH	570..707	CDD:128594	48/154 (31%)
VPS41	NP_172297.2	WD40	<59..270	CDD:441893	80/223 (36%)
		WD40 repeat	63..96	CDD:293791	13/38 (34%)
		WD40 repeat	102..138	CDD:293791	16/35 (46%)
		WD40 repeat	143..186	CDD:293791	17/44 (39%)
		WD40 repeat	191..222	CDD:293791	12/30 (40%)
		WD40 repeat	229..270	CDD:293791	13/43 (30%)
		CLH	613..765	CDD:128594	48/153 (31%)
		RING-H2_Vps8	886..972	CDD:438348	15/53 (28%)