Protein Alignment CG17715 and TMEM65

DIOPT Version :9

• Sequence 1: NP_001036410.1
• Gene: CG17715 / 3355129
• FlyBaseID: FBgn0041004
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_919267.2
• Gene: TMEM65 / 157378
• HGNCID: 25203
• Length: 240
• Species: Homo sapiens
• Alignment Length: 134
• Identity: 66/134 - (49%)
• Similarity: 90/134 - (67%)
• Gaps: 2/134 - (1%)

  Fly   137 AASPTAGQLYSIFFVNAVPFIAFGFLDNFIMIMAGEYIEYYLGHFITLSTMAAAGLGNTISDILG 201
            |..||.|||..:|..||:|||.||||||.|||:||.:||..:|..:.:||||||.|||.:||:.|
Human   106 APPPTPGQLRYVFIHNAIPFIGFGFLDNAIMIVAGTHIEMSIGIILGISTMAAAALGNLVSDLAG 170

  Fly   202 ITMATYVENGCQILGLKQPNLTPAQFELKSSKRSSSYGRIVGITVGCLLGMCPLWFM--DEKADK 264
            :.:|.|||.....|||..|:|||.|.::..::.|:..|:.||:|:||:|||.||.|.  .|:.:|
Human   171 LGLAGYVEALASRLGLSIPDLTPKQVDMWQTRLSTHLGKAVGVTIGCILGMFPLIFFGGGEEDEK 235

  Fly   265 VNVK 268
            :..|
Human   236 LETK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17715	NP_001036410.1	DUF2453	151..258	CDD:287478	55/106 (52%)
TMEM65	NP_919267.2	DUF2453	120..227	CDD:287478	55/106 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144807
Domainoid	1	1.000	115	1.000	Domainoid score	I6031
eggNOG	1	0.900	-	-		E1_KOG4619
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D573372at33208
OrthoFinder	1	1.000	-	-		FOG0006142
OrthoInspector	1	1.000	-	-		oto89432
orthoMCL	1	0.900	-	-		OOG6_104678
Panther	1	1.100	-	-	LDO	PTHR21706
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4172
SonicParanoid	1	1.000	-	-		X4432
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.740