Protein Alignment Slmap and VPS64

DIOPT Version :9

• Sequence 1: NP_001036397.2
• Gene: Slmap / 3355127
• FlyBaseID: FBgn0040011
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_010486.3
• Gene: VPS64 / 851781
• SGDID: S000002608
• Length: 604
• Species: Saccharomyces cerevisiae
• Alignment Length: 607
• Identity: 126/607 - (20%)
• Similarity: 233/607 - (38%)
• Gaps: 164/607 - (27%)

  Fly    97 SNNEASTKNQE------------NNNMELCDSNTVCIDR--------------RPAEVSQHAMNM 135
            ||::..||..|            :|:......:.|.||:              .|..|.|.:...
Yeast    24 SNSQGMTKTPETSPPKRPMGRARSNSRSSGSRSNVDIDQYTIPPGLDLLPTASSPPSVHQVSQQQ 88

  Fly   136 AMNSVLNANNTGVGVRVTTACSLFSPLGVLNNSALQREVASECGTLQVSSVPPTSGVDLDIGLES 200
            .::.:|             |..:.||..  |.|..|.:          :|:.||....:.|.:|:
Yeast    89 QLSPIL-------------ANKIRSPFE--NQSQDQND----------NSIDPTPAGQVTIPVEA 128

  Fly   201 APTPC--------KGAAKI-------------VLLCEPKSHKFETRSILLQPNQD-CKVGRLIAK 243
            ...|.        .|:.:.             :::.:..:..|||:.:::....| .|:||.:..
Yeast   129 VSPPALDELSKFQNGSTETLFRTGSPRKKHTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTN 193

  Fly   244 S--KAGEG-------------NAIFDCKVLSRNHAILWYTP-DGKFWVKDTKSSNGTFINDNKLG 292
            |  |...|             |..||.:|||||||.|...| .||.:::|.|||||||:|..|:.
Yeast   194 SVNKNNSGSKRDLFSQQVRPDNGNFDSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIR 258

  Fly   293 SDPAELHYGDIVKFGVEVIENSRQEVHGCILARVALFLPNGQEAISVEAEQMMLTVPNRISFDEV 357
            .:..||..||.|..|.::  :|:.| |..|.|.|        |.|||        :|...:..:.
Yeast   259 QNDVELKVGDTVDLGTDI--DSKFE-HRKISAYV--------EEISV--------IPLMNTVSDP 304

  Fly   358 QRLSSFLQEAAQREKSLKAKLSSLQGVLDNTRKN-------------------SAMCWQSMITED 403
            ..|....|:...:.......::.::  :|....|                   ||...|....|.
Yeast   305 TNLVMKKQDHTNKNNGNSTNINGIK--IDRGHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEA 367

  Fly   404 QLLHKIN-------ILEKKLQMMEKNIPENALRNEI--VKLLEDKTTYQLTAKEALRKVY----- 454
            .:...||       ||..:.:::......|:....|  :.:::..||.....|:.|.|::
Yeast   368 AMFGDINNSELDDDILGPETEVLSGIFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNF 432

  Fly   455 -QERCDAMQMLSKMEMAYATSENECGILRAQVLTLKQTLTDFN-TRLEELQQEYMEFKKESVRQE 517
             |.....:..::|    :....||..:|:... .|::||::.| ..|:|.:.:..|.|:::.:.:
Yeast   433 MQNYTINLDFINK----HMIDMNEKHLLKLST-ALQKTLSENNDALLKESEDQLKEIKQQNNKVK 492

  Fly   518 QEAKEQESRSLEVLNGKLTTQELELKELRLQVSRIHRDLSESDTEHLKERIVLKNLDTINLDDYD 582
            .....:|.::.|    ||...|.||:||.||:          :.|..|..::.::.....:::.:
Yeast   493 SACSLKEKQNHE----KLQELESELRELNLQI----------EEERGKNLVLTQSNFNGGINNDN 543

  Fly   583 HAQDRALNERDDNESSDDDILS 604
            :|:.:..:.|::.:.::|.::|
Yeast   544 NAKVKQNDSREEKKDTEDTLIS 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slmap	NP_001036397.2	FHA	216..311	CDD:238017	40/111 (36%)
		FHA	<225..326	CDD:224630	42/117 (36%)
VPS64	NP_010486.3	FHA	126..304	CDD:224630	54/196 (28%)
		SMC_prok_B	<406..>580	CDD:274008	35/179 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I2465
eggNOG	1	0.900	-	-		E1_COG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003045
OrthoInspector	1	1.000	-	-		otm46962
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15715
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R322
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030