Protein Alignment Slmap and TRAF3IP3

DIOPT Version :9

• Sequence 1: NP_001036397.2
• Gene: Slmap / 3355127
• FlyBaseID: FBgn0040011
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001307072.1
• Gene: TRAF3IP3 / 80342
• HGNCID: 30766
• Length: 551
• Species: Homo sapiens
• Alignment Length: 643
• Identity: 132/643 - (20%)
• Similarity: 216/643 - (33%)
• Gaps: 200/643 - (31%)

  Fly    95 ADSNNEASTKNQENNNMELCDSN-TVC-----------------------IDRRPAEV-----SQ 130
            |:|......:.||......|..| |.|                       ..||..|:     :|
Human    16 AESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQ 80

  Fly   131 HAMNMAMNSVLNANNTGVGVRVTTACSLFSPLGVLNNSALQRE-VASECGTLQVSSVPPTSGVDL 194
            |.         .|...|...|......|..||......:..|| |......:..:..||.||:..
Human    81 HP---------QAREQGPSRRPGQVTVLKEPLSCARRISSPREQVTGTSSEVFPAQHPPPSGICR 136

  Fly   195 DI---------GLESAPTPCKGAAKIVLLCEPKSHKFETRSILLQPNQDCKVGRLIAKSKAGEGN 250
            |:         ||....||.|         :|..|...|:
Human   137 DLSDHLSSQAGGLPPQDTPIK---------KPPKHHRGTQ------------------------- 167

  Fly   251 AIFDCKVLSRNHAILWYTPDGKFWVKDTKSSNGTFINDNKLGSDPAELHYGDIVKFGVEVIENSR 315
                                       ||:...|..||....::           :||.|::.
Human   168 ---------------------------TKAEGPTIKNDASQQTN-----------YGVAVLDK-- 192

  Fly   316 QEVHGCILARVALFLPNGQEAISVEAEQMMLTVPNRISFDEVQRLSSFLQEAAQREKSLKAKLSS 380
                                                    |:.:||.:|:||.|||..||.|:..
Human   193 ----------------------------------------EIIQLSDYLKEALQRELVLKQKMVI 217

  Fly   381 LQGVLDNTRKNSAMCWQSMITEDQLLHKINILEKKLQMMEKNIPENALRNEIVKLLEDKTTYQLT 445
            ||.:|....:.|...|:..:.||:|..|:..||.:|....:......::..::::.:.|.:|:..
Human   218 LQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQK 282

  Fly   446 AKEALRKVYQERCDAMQMLSKMEMAYATSENECGILRAQVLTLKQTLTDFNTRLEELQQEYMEFK 510
            |||:|:||.:|:.:|.|.|...:.:.|.:|.:|...|:|...||:......|:..||
Human   283 AKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHREL-------- 339

  Fly   511 KESVRQEQEAKEQ--ESRSLEVLNGKLTTQELELKELRLQVSRIH--RDLSESDTEHLKERIVLK 571
             ||.....::|.|  :||.|: :|..|...|.|.::|:.::..:.  |||...||:.|::::...
Human   340 -ESQLHVLQSKLQGADSRDLQ-MNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRS 402

  Fly   572 NLDTI-------NLDDYDHAQDRALNERDDNESSDDDILSVSPAKNVLSE-----TKKRKLKLSN 624
            ..:.:       .|......|...|.|::...:..|..|.|...|:..:|     |.|.|    :
Human   403 EAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEK----D 463

  Fly   625 PDLEEGNYKSNVLRLLKNSDLGKGEEGSSVLKAIFNGDDEAFEC--KVKEEEDMANDS 680
            .||.: ..:...|:|     ..|.:|...:...:.|..||...|  |::...:..|.|
Human   464 WDLRD-QLQKKTLQL-----QAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slmap	NP_001036397.2	FHA	216..311	CDD:238017	10/94 (11%)
		FHA	<225..326	CDD:224630	8/100 (8%)
TRAF3IP3	NP_001307072.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..95		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..178		11/98 (11%)
		Smc	201..>517	CDD:224117	86/335 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157112
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15715
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940