Protein Alignment Slmap and rnf8

DIOPT Version :9

• Sequence 1: NP_001036397.2
• Gene: Slmap / 3355127
• FlyBaseID: FBgn0040011
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_991116.1
• Gene: rnf8 / 404050
• ZFINID: ZDB-GENE-040426-849
• Length: 531
• Species: Danio rerio
• Alignment Length: 612
• Identity: 130/612 - (21%)
• Similarity: 227/612 - (37%)
• Gaps: 163/612 - (26%)

  Fly   181 LQVSSVPPTSGVDLDIGLESAPTPCKGAAKIVLLCEPKSHKFETRSILLQPNQDCKVGRLIAKSK 245
            ::.:..||:|..:     |.:|      ||..:.|            |.:..:|....||...|:
Zfish     1 MEKTEEPPSSNNE-----EDSP------AKEKIWC------------LQRVGRDSDWLRLFEDSE 42

  Fly   246 AGEGNAI--------FDCK-VLSRNHAILWYTPDGKFW-VKDTKSSNGTFINDNKL-GSDPAELH 299
            ...|..:        ..|. ::||.|.: :...:|:.| |.|.||.||.::|..:: .|.|..||
Zfish    43 VSVGRGLNVTHQILSSSCPLMISRIHCV-FKLNEGRQWTVTDNKSLNGVWVNGKRIPPSTPCILH 106

  Fly   300 YGDIVKFGVEVIENSRQEVHGCILAR----VALFLPN--GQEAISVEAEQMMLT----------- 347
            ..|.|:.||. ::.:..|....::.:    |..||..  |:::.:....|.:..
Zfish   107 QSDSVRLGVP-LDGNPVEFDYILVQKNFNDVKSFLSGNLGKDSGAASLSQKLKNSKRKFDGGDES 170

  Fly   348 --VPNRISFDEVQRLSSFLQEAAQ------REKSLKAKLSSLQGVLDNTRKNSAMC---WQSMIT 401
              .|.:.|..::.|.|:..:..||      |.::||.....|:...|....:|:.|   .|.:.|
Zfish   171 EPCPTQHSKSKLYRSSAPDKSRAQPCPSGERRETLKLSSRPLEEDRDKAGSSSSTCSDSSQHLAT 235

  Fly   402 EDQLLHKIN----ILE----------KKLQMMEKNIPENALRNEIVKLLEDKTTYQLTAKEALRK 452
                ||:.|    :|:          .:|:..:...||..      |.::|..| ||.|.....:
Zfish   236 ----LHRYNRSLMVLKGRVGDTQKRAAELEQQQTQTPERE------KEMQDLQT-QLEALRGQLR 289

  Fly   453 VYQERCDAMQMLSKMEMAYATSE----------NECGILRAQVLTLKQTLTDFNTRLEELQQEYM 507
            ..||:  |::.:..:|.::...|          ||.|:.:    .|::.|.:....:|||:....
Zfish   290 SQQEQ--ALRRMETLEKSFCEEERRLETEKAQQNEVGLKK----QLEEALKEHRKVIEELKHARQ 348

  Fly   508 EFKK--ESVRQEQEAKEQESRSLEVLNGKLTTQELELKELRLQVSRIHRDLSESDTEHLKERIVL 570
            .||:  ::..:|.|..::|....:....::.||..|:.|..||.|..        :|...|.:.|
Zfish   349 GFKEVLQAKDKELEVTKEEKEKAKAQKEEVVTQMTEVLESELQCSIC--------SELFIEAVTL 405

  Fly   571 KNLDTINLDDYDHAQDRALNERDDNESSDDDILSVSPA--KNVLSETKKRKLKLSN--------- 624
            ....:.    ..|......|.:|.           .|.  :|:.|:|  |.|.|.|
Zfish   406 NCAHSF----CQHCISEWRNRKDK-----------CPMCWQNITSQT--RSLVLDNCIDRMVENL 453

  Fly   625 -PDLEEGNYKSNVLRLLKNSDLGKGEEGSSVLKAIFNGDDEAFECKVKEEEDMANDSVPTEFVSR 688
             .|:.|...      :|.|...|.....|..: .:.|.|.::        ||.::....| |:..
Zfish   454 SADMRERRL------VLINERKGLKVRASPAV-VVINDDSDS--------EDSSSSDGDT-FLQS 502

  Fly   689 NTSEIVDHFKNHSSTTHTILEDSAATK 715
            |:|...|   :..|....|||||:.|:
Zfish   503 NSSIFPD---SSGSDDSLILEDSSWTE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slmap	NP_001036397.2	FHA	216..311	CDD:238017	27/105 (26%)
		FHA	<225..326	CDD:224630	28/115 (24%)
rnf8	NP_991116.1	FHA	23..115	CDD:238017	26/104 (25%)
		FHA	<26..114	CDD:224630	24/88 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..232		14/81 (17%)
		GBP_C	<263..362	CDD:303769	24/111 (22%)
		coiled coil	339..349	CDD:293879	3/9 (33%)
		RING	391..433	CDD:238093	9/64 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900