DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slmap and slmap

DIOPT Version :9

Sequence 1:	NP_001036397.2	Gene:	Slmap / 3355127	FlyBaseID:	FBgn0040011	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	XP_031755654.1	Gene:	slmap / 100135075	XenbaseID:	XB-GENE-952522	Length:	823	Species:	Xenopus tropicalis

Alignment Length:	712	Identity:	214/712 - (30%)
Similarity:	347/712 - (48%)	Gaps:	145/712 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 AAKIVLLCEPKSHKFETRSILLQPNQDCKVGRLIAKSKAGEGNAIFDCKVLSRNHAILWYT-PDG 271
            :|..:..|.|.||.|:.|.:.|  ::..|:||.:|:.:..:.||.|||||||||||::|:. ..|
Frog     3 SALAIFTCRPNSHPFQERHVYL--DEPVKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTG 65

  Fly   272 KFWVKDTKSSNGTFINDNKLG-----SDPAELHYGDIVKFGVEVIENSRQEVHGCILARVALFLP 331
            ||:::|||||||||||..:|.     |.|.|:..|||::|||:|.||:|:..||||::.|.||||
Frog    66 KFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGCIVSTVKLFLP 130

  Fly   332 NGQE----------AISVEAEQMMLTVPNRISFDEVQRLSSFLQEAAQREKSLKAKLSSLQGVLD 386
            :|.|          |:....:::....|:..| .|:.:||.:||||..||:.|:.||::||.:|.
Frog   131 DGLETRRRSDVIPAALPSPIDKVAAHTPSMYS-QELFQLSQYLQEALHREQMLEQKLATLQRLLA 194

  Fly   387 NTRKNSAMCWQSMITEDQLLHKINILEKKLQMMEKNIPENALRNEIVKLLEDKTTYQLTAKEALR 451
            ||::.|...||::|.||:||.::.::..:||...|:..::.:|.|::.|.|||..|:.||||:||
Frog   195 NTQEASDTSWQALIDEDRLLSRLEVMGNQLQAYSKSQTDDGIRKEMIALQEDKHNYETTAKESLR 259

  Fly   452 KVYQERCDAMQMLSKMEMAYATSENECGILRA---------------------QVLTLKQTLTDF 495
            :|.||:.:.::.||::|.:.:.:|:||..|:.                     ::..|...|...
Frog   260 RVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLADKLKAA 324

  Fly   496 NTRLEELQQEYMEFKKESVRQ--EQEAKEQESRS-LEVL--NGKLTTQELELKELRLQVSRIHRD 555
            .:|.||:||:.:..|||...:  |.|.||||.:: :|.|  :...|.:.|...::||
Frog   325 ESRQEEIQQKALAEKKELQNKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRL-------- 381

  Fly   556 LSESDTEHLKERIVLKNLDTINLDDYDHAQDRALNERDDNESSDDDILSVSPAKNVLSETKKRKL 620
                  |||:|: .||..:::.:...|...  .:|...|.:...|..|       :..:.::::|
Frog   382 ------EHLQEK-TLKEHNSLGIQVGDFIP--KINGNADKDKLIDQHL-------IRGDQERQRL 430

  Fly   621 KLSNPDLEEGNYKSNVLRLLKNSDLGKGEEGSSVLKAIFNGDDEAFECKVKEEEDMANDSVPTEF 685
            |.|.|:.:|.:.         :..|...:|.||        ||...:.::.|:|
Frog   431 KESPPEAKESDL---------SDTLSPSKEKSS--------DDTTADGQMDEQE----------- 467

  Fly   686 VSRNTSEIVDHFKNHSSTTHTILEDSAATKLSAPNAESKEKLVDV-EENLNIPNALPTE------ 743
                        .|.|....|:|:|..   |.|...|:|.::..: :|.|....||.|.
Frog   468 ------------LNESPNKVTLLKDEL---LHAGANEAKPEIQQLHKELLEAQEALRTSKQKCLE 517

  Fly   744 -QAIDMLQEE-------CDTYKKKTAHLTSEIHFLQGQIELLKKQLEK--GVDHNFATNLQEEEN 798
             ||  :|:||       .:...|:..||.:::..||.:||:|::|.|.  |.......:.|||..
Frog   518 LQA--LLEEESRAGRQQAEESTKQIQHLQAQLQRLQKEIEVLREQKENEIGSTREALLHAQEEIE 580

  Fly   799 SLPRETLELIDNRDSTEGVWNEDIATINNPNVENEEELIVYKELLENSELNNMQLRKEISEL 860
            .|.|.:.::...|:.       |||       |.:.||...:..||:......|..|||..|
Frog   581 ILKRVSEQVASEREG-------DIA-------ELQGELQEVRFELEHWRKAASQYEKEIENL 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slmap	NP_001036397.2	FHA	216..311	CDD:238017	48/100 (48%)
Slmap	NP_001036397.2	FHA	<225..326	CDD:224630	52/106 (49%)
slmap	XP_031755654.1	FHA	14..108	CDD:238017	46/95 (48%)
		SMC_prok_B	<163..790	CDD:274008	146/549 (27%)
		CC1_SLMAP	163..225	CDD:409287	25/61 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I4404
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3223
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003045
OrthoInspector	1	1.000	-	-		oto105493
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R322
SonicParanoid	1	1.000	-	-		X5155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.080