DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL5 and rpl5b

DIOPT Version :9

Sequence 1:	NP_001036387.1	Gene:	RpL5 / 3355124	FlyBaseID:	FBgn0064225	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001002106.1	Gene:	rpl5b / 415196	ZFINID:	ZDB-GENE-040625-93	Length:	296	Species:	Danio rerio

Alignment Length:	298	Identity:	207/298 - (69%)
Similarity:	244/298 - (81%)	Gaps:	2/298 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGFVKVVKNKQYFKRYQVKFRRRREGKTDYYARKRLTFQDKNKYNTPKYRLIVRLSNKDITVQIA 65
            ||||||||||.|||||||||||||||||||:|||||..||||||||||||:|||.||:||..|||
Zfish     1 MGFVKVVKNKSYFKRYQVKFRRRREGKTDYFARKRLVIQDKNKYNTPKYRMIVRFSNRDIVCQIA 65

  Fly    66 YARIEGDRVVCAAYSHELPKYGIQVGLTNYAAAYCTGLLVARRVLNKLGLDSLYAGCTEVTGEEF 130
            ||:||||.:||||||||||||||.|||||||||||||||:|||:|||.|||.:|.|..|:||:||
Zfish    66 YAKIEGDMIVCAAYSHELPKYGISVGLTNYAAAYCTGLLLARRLLNKFGLDKVYDGQVEITGDEF 130

  Fly   131 NVEPVDDGPGAFRCFLDVGLARTTTGARVFGAMKGAVDGGLNIPHSVKRFPGYSAETKSFNADVH 195
            |||.:|..||||.|:||.||||||||.:||||:||||||||:||||.||||||..|:|.|||:||
Zfish   131 NVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDVESKEFNAEVH 195

  Fly   196 RAHIFGQHVADYMRSLEEEDEESFKRQFSRYIKLGIRADDLEDIYKKAHQAIRNDPTHKVTAKKS 260
            |.||.|.::|:|||.|.|||||.:|:||||:||.|:.||.:|::|||||.|||.:|.|:...|:.
Zfish   196 RKHILGLNIAEYMRLLMEEDEECYKKQFSRFIKNGVTADSMEEMYKKAHAAIRENPVHEKKPKRE 260

  Fly   261 SAVTKKRWNAKKLTNEQRKTKIAAHKAAYVAKLQSETE 298
              |.|||||..|||..|||.::|..||:::....:|.:
Zfish   261 --VKKKRWNRAKLTLAQRKDRVAQKKASFLRAQAAEED 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL5	NP_001036387.1	PTZ00069	1..298	CDD:240254	207/296 (70%)
rpl5b	NP_001002106.1	PTZ00069	1..295	CDD:240254	206/295 (70%)
		Ribosomal_L18p	26..173	CDD:279233	114/146 (78%)
		Ribosomal_L18_c	192..282	CDD:290906	51/91 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580871
Domainoid	1	1.000	277	1.000	Domainoid score	I1695
eggNOG	1	0.900	-	-		E1_COG0256
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110649
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1667
OMA	1	1.010	-	-		QHG53582
OrthoDB	1	1.010	-	-		D405247at33208
OrthoFinder	1	1.000	-	-		FOG0002632
OrthoInspector	1	1.000	-	-		otm25383
orthoMCL	1	0.900	-	-		OOG6_100789
Panther	1	1.100	-	-	LDO	PTHR23410
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1142
SonicParanoid	1	1.000	-	-		X1734
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	16	15.840