DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL5 and rpl-5

DIOPT Version :9

Sequence 1:	NP_001036387.1	Gene:	RpL5 / 3355124	FlyBaseID:	FBgn0064225	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_495811.1	Gene:	rpl-5 / 174371	WormBaseID:	WBGene00004416	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	299	Identity:	179/299 - (59%)
Similarity:	229/299 - (76%)	Gaps:	7/299 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGFVKVVKNKQYFKRYQVKFRRRREGKTDYYARKRLTFQDKNKYNTPKYRLIVRLSNKDITVQIA 65
            ||.|||:|||.||||||||.|||||||||||||||||.||||||||||||||||::|||:..|:|
Worm     1 MGLVKVIKNKAYFKRYQVKLRRRREGKTDYYARKRLTVQDKNKYNTPKYRLIVRITNKDVVAQLA 65

  Fly    66 YARIEGDRVVCAAYSHELPKYGIQVGLTNYAAAYCTGLLVARRVLNKLGLDSLYAGCTEVTGEEF 130
            |::||||.||.:|||||||:||::||||||||||.||||:|||.|..:||||.|.|..|:|||::
Worm    66 YSKIEGDVVVASAYSHELPRYGLKVGLTNYAAAYATGLLLARRHLKTIGLDSTYKGHEELTGEDY 130

  Fly   131 NVEPVDDGPGA-FRCFLDVGLARTTTGARVFGAMKGAVDGGLNIPHSVKRFPGYSAETKSFNADV 194
            |||  ::|..| |:..||:||||||||:::|..|||..|||:|:|||..||.|:..|:|.:||:.
Worm   131 NVE--EEGDRAPFKAVLDIGLARTTTGSKIFAVMKGVADGGINVPHSESRFFGFDQESKEYNAEA 193

  Fly   195 HRAHIFGQHVADYMRSLEEEDEESFKRQFSRYIKLGIRADDLEDIYKKAHQAIRNDPTHKVTAKK 259
            ||..|.|:||||||..|:||||:.:|||||:::..|:.||:|...|:|.|.|||.|.:   .|.|
Worm   194 HRDRILGKHVADYMTYLKEEDEDRYKRQFSKFLAAGLNADNLVATYQKVHSAIRADAS---PAAK 255

  Fly   260 SSAVTKKRWNAKKLTNEQRKTKIAAHKAAYVAKLQSETE 298
            .:|...||..||:||.::||.:: |.|.|.:.:|:.:.|
Worm   256 KAAKPSKRHTAKRLTYDERKQRV-ADKKALLLQLKEQQE 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL5	NP_001036387.1	PTZ00069	1..298	CDD:240254	178/297 (60%)
rpl-5	NP_495811.1	PTZ00069	1..287	CDD:240254	177/291 (61%)
		Ribosomal_L18p	26..172	CDD:279233	100/147 (68%)
		Ribosomal_L18_c	191..279	CDD:290906	43/91 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159465
Domainoid	1	1.000	240	1.000	Domainoid score	I1267
eggNOG	1	0.900	-	-		E1_COG0256
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110649
Inparanoid	1	1.050	361	1.000	Inparanoid score	I1283
Isobase	1	0.950	-	0	Normalized mean entropy	S338
OMA	1	1.010	-	-		QHG53582
OrthoDB	1	1.010	-	-		D405247at33208
OrthoFinder	1	1.000	-	-		FOG0002632
OrthoInspector	1	1.000	-	-		oto18673
orthoMCL	1	0.900	-	-		OOG6_100789
Panther	1	1.100	-	-	LDO	PTHR23410
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1142
SonicParanoid	1	1.000	-	-		X1734
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790