Protein Alignment CG40006 and SCARB1

DIOPT Version :10

• Sequence 1: NP_001036401.1
• Gene: CG40006 / 3355123
• FlyBaseID: FBgn0058006
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_001354910.1
• Gene: SCARB1 / 949
• HGNCID: 1664
• Length: 552
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 130/457 - (28%)
• Similarity: 224/457 - (49%)
• Gaps: 27/457 - (5%)

  Fly    96 VIGFLAIITSTLIKVLEPYDLIFKWKLI----MTEGGEIFNLWAQPPVDLYIKIYLFNITNANAF 156
            |.|.|..:...::.|:.|  .:.|.:::    :......||:|.:.|:..|:.:|.|::.|.:..
Human    16 VAGLLCAVLGAVMIVMVP--SLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPSEI 78

  Fly   157 LAGREQLRVEQVGPYVYKEIMTHENVTFNSNNTMSSTPSHPLVWQEEMSGNCREDDEVVMLNIAM 221
            |.| |:.:|.:.|||||:|.....|:|||:|:|:|........:|...| :..|.|.:||.||.:
Human    79 LKG-EKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKS-HGSESDYIVMPNILV 141

  Fly   222 LAISHLTANQPFLVRMALKTLLLSTKSE-PIVRTTAKEFMFGYPSALATLGNTFLPNWISF-EKV 284
            |..:.:..|:|..::: :.||..:|..| ..:..|..|.|:||...|..|.|.:.|....| :|.
Human   142 LGAAVMMENKPMTLKL-IMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPFKDKF 205

  Fly   285 GLIDRMYDFSTDFETFYTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDGTKFKSFIQPN 349
            ||...:.:..:...|.:|||.|.:...|...:.|.:.:..|..|.|:.|. .:.|..:..|:.|.
Human   206 GLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMIN-GTSGQMWPPFMTPE 269

  Fly   350 ETVKFFRKSMCRPINLYRVGNEKTYGSLKG---YNYVFEDNAFDNGATNEANKCFCRKGDCQPVG 411
            .:::|:....||.:.|.    .|..|..:|   |.:|.....|.||:....|:.||   .|...|
Human   270 SSLEFYSPEACRSMKLM----YKESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFC---PCLESG 327

  Fly   412 LIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGLPLSLSVKVQINM 476
            :.:|:.|.:..|:.||.|||:|.|..|.:.|||:.|:.:.||....|.|.:|:|::.|||:|:::
Human   328 IQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSL 392

  Fly   477 HFKDLSNFPVVSVFNHLTVPMLWFEIMMSKLPDSLDSRFNFY--LNILPLVNPLGFWSGILLGIS 539
            :.|.::..........:.:|:|||....:...::|.:   ||  |.::|.|.....:..:.||..
Human   393 YMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHT---FYTQLVLMPKVMHYAQYVLLALGCV 454

  Fly   540 LL 541
            ||
Human   455 LL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	96..545	CDD:460076	130/457 (28%)
SCARB1	NP_001354910.1	CD36	16..446	CDD:460076	126/445 (28%)