DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40006 and scarb2b

DIOPT Version :9

Sequence 1:	NP_001036401.1	Gene:	CG40006 / 3355123	FlyBaseID:	FBgn0058006	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	512	Identity:	146/512 - (28%)
Similarity:	240/512 - (46%)	Gaps:	33/512 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LLVIGFLAIITSTLIKVLEPYDLIFKWKLIMTEGGEIFNLWAQPPVDLYIKIYLFNITNANAFLA 158
            ||::..:|:..|.|.:.|....|  |.::.:|||.::|..|..||..:|::.:.||:||..|||.
Zfish    17 LLLLAGIALFASGLFQTLIHNKL--KKEITLTEGSKVFATWKNPPPPVYMEFFFFNVTNPEAFLK 79

  Fly   159 GREQLRVEQVGPYVYKEIMTHENVTFNSNNT--MSSTPSHPLVWQEEMSGNCREDDEVVMLNIAM 221
            |..:.|:.::|||.|:|.....||:|..|.|  .:.||. ..|:..|.|......|.|..:||..
Zfish    80 GEAKARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPK-VFVFVPEKSVGDPSVDMVTTVNIPA 143

  Fly   222 LAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFGYPSALATLGNTFLPNWISFEKVGL 286
            :|:.:......|||..|:...:.|..:|..:..|..|.::|:...|.|...:..|....|  .||
Zfish   144 VAVMNRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLWGFKDPLLTKLRSIKPETDEF--FGL 206

  Fly   287 IDRMYDFSTDFE-TFYTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDGTKFKSFIQPNE 350
            :... :.|.|.| .::||..|....|...:::||..:..|..:. ||:...:||:.|..|:...|
Zfish   207 MLHK-NGSDDGEFVYHTGEHNYLDYGRIFTWKGEKLMSFWKTNQ-SNMINGTDGSAFHPFLTKEE 269

  Fly   351 TVKFFRKSMCRPINLYRVGNEKTYGSLKGYNYVFEDNAFDNGATNEANKCFC---RKGDCQPVGL 412
            .:..|...:||.|:: |...|.....:..|.:........:|..|..|:.||   :|  |...|:
Zfish   270 RLDVFTADLCRSIHM-RFEKEVEVKGIPAYRFTPPRAVLASGTNNPENEGFCLTPKK--CLDDGV 331

  Fly   413 IDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGLPLSLSVKVQINMH 477
            :||:.|..|.|:.:|||||..||....|.|.|:||..::|.:...:.|..|:|:....:.|||:|
Zfish   332 LDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFLDLNPTMGVPVRAMKRAQINIH 396

  Fly   478 FKDLSNFPVVSVFNHLTVPMLWFEIMMSKLPDSLDS-RFNFYLNILPLVN--PLGFWSGILLGIS 539
            .:.::.||:.........|:::  :..|.:.|:..: |....|.::.||:  ||..   :.||:.
Zfish   397 LERVTGFPMTRNLESTIFPIIF--LNESVVIDNASAERIQKLLLVVTLVSHFPLIL---VALGVI 456

  Fly   540 LLGYAITKATLHMSTFSRRAANITDVK-YVRANLIQNIAGEA-ANHAYSPCDIKLLD 594
            ||..|:..|.       |...|.|:|| :..|......|..| .:.:|:|...|:.|
Zfish   457 LLIVAVILAV-------RYYQNKTEVKRFDFAEAFHCTAPSAKKDTSYAPVSAKVDD 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	132/459 (29%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	129/447 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020