DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG40006 and scarb1

DIOPT Version :9

Sequence 1:	NP_001036401.1	Gene:	CG40006 / 3355123	FlyBaseID:	FBgn0058006	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	XP_017213428.1	Gene:	scarb1 / 387260	ZFINID:	ZDB-GENE-031126-1	Length:	511	Species:	Danio rerio

Alignment Length:	519	Identity:	147/519 - (28%)
Similarity:	238/519 - (45%)	Gaps:	37/519 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 ILLVIGFLAIITSTLIKVLEPY---DLIFKWKLIMTEGGEIFNLWAQPPVDLYIKIYLFNITNAN 154
            :.||:|.:|::..|::..:.|.   |.|.|...|..:....:.:|...||..::.:|.|:|.|.:
Zfish    10 VFLVLGGMALLFGTVLVFVGPIIIDDQIVKNVEINPKNDLSYTMWKDIPVPFFMSVYFFHIVNPD 74

  Fly   155 AFLAGREQLRVEQVGPYVYKEIMTHENVTFNSNNTMSSTPSHPLVWQEEMS-GNCREDDEVVMLN 218
            ..|.| |:..|.|.|||||:|....:|:||:.|:|:|........::|.|| |:  |.|.|.:.|
Zfish    75 EILKG-ERPMVIQRGPYVYRENRWKDNITFHENHTVSYKEYRQYFFEESMSVGD--ESDVVTIPN 136

  Fly   219 IAMLAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFGYPSALATLGNTFLPNWI-SFE 282
            :.:|..|.:..|.||.||:.|.|...:....|.:.....|.|:||.|.|....|.:||..: |..
Zfish   137 MLVLGASVMMENMPFPVRLLLSTTFKTFNEGPFLTKPVGELMWGYDSKLVDFLNKYLPGMLPSSG 201

  Fly   283 KVGLIDRMYDFSTDFETFYTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDGTKFKSFIQ 347
            |.||.....:.:|...|.:||..:.....:..|:.|...:..|..|.|:.|. .:.|..:..|:.
Zfish   202 KFGLFADFNNSNTGLFTIFTGRDDIRKVHMVDSWNGLKNVDYWRSDQCNMIN-GTAGQMWPPFMT 265

  Fly   348 PNETVKFFRKSMCRPINL-YRVGNEKTYGSLKGYNYVFEDNAFDNGATNEANKCFCRKGDCQPVG 411
            ...|:.|:....||.:.| |:  .......:..|.||.....|.|||....|:.||   .|:..|
Zfish   266 KETTMPFYSPDACRSMELVYQ--RPLVSSGIPVYRYVSPKTLFANGADFPPNEGFC---PCRQSG 325

  Fly   412 LIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGLPLSLSVKVQINM 476
            |::|:.|.:|.|..:|.|||.|.|..|...|:|:||..|:|.....|.||:|:|:::||::|:|:
Zfish   326 LLNVSSCRHGSPTFISQPHFYNADPQLLDTVSGLSPSEDEHGLFIDIHPETGVPVNVSVRLQLNL 390

  Fly   477 HFKDLSNFPVVSVFNHLTVPMLWFEIMMSKLPDSLDSRFNFYLNILPLVNPLGFWSGILLGISLL 541
            ..|.:|..........:.:|||||| ....:...:...|...|.:||.|.....:..|.||::.:
Zfish   391 FLKKVSGISETGNIAEVVMPMLWFE-ESGYIDGPVLHTFRTNLVVLPKVMEYMQYIFIALGLAAI 454

  Fly   542 GYAITKATLHMSTFSRRAANITDVKYVRANLIQNIAGEAANHAYSPCDIKLLDDISVVRHPVNK 605
            ..|:.........:.:.:..:|..  |...:..|:     ||:              .:||.|:
Zfish   455 LTAVILFLTDKKVWKKSSQTLTQA--VSTRVYDNV-----NHS--------------KQHPANE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	138/457 (30%)
scarb1	XP_017213428.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950