DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40006 and emp

DIOPT Version :9

Sequence 1:	NP_001036401.1	Gene:	CG40006 / 3355123	FlyBaseID:	FBgn0058006	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_726504.2	Gene:	emp / 37999	FlyBaseID:	FBgn0010435	Length:	551	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	154/555 - (27%)
Similarity:	265/555 - (47%)	Gaps:	63/555 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 IQGKRNRVPTRL--------FILLVIGFLAIITSTLI----KVLEPYDLIFKWKLIMTEGGEIFN 132
            :.|.:::..|:|        :|.:|:....||...::    .||  .|.:....:.:..|.:.|.
  Fly    32 MNGPKHKFCTKLSSTYLRKWWITIVVAAALIIGGIVVACEFTVL--IDAVVDRMVALRPGAKTFG 94

  Fly   133 LWAQPPVDLYIKIYLFNITNANAFLAGREQLRVEQVGPYVYKEIMTHENVTFNSNNTMSSTPSHP 197
            .||:|||:..|.:|::|:|||:.||:...:..|::||||||.|.....|:..|.|.|:|......
  Fly    95 WWAKPPVEPRISLYIYNVTNADDFLSNGSKAIVDEVGPYVYSETWEKVNIVENDNGTLSYNLRKI 159

  Fly   198 LVWQEEMSGNCREDDEVVMLNIAMLAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFG 262
            ..::|::|.. .|||.|::.||.||:.:..:.:....:|:|:.:::...|.:|.|:.:..:.::|
  Fly   160 YSFREDLSVG-PEDDVVIVPNIPMLSATSQSKHAARFLRLAMASIMDILKIKPFVQVSVGQLLWG 223

  Fly   263 YPSALATLGNTFLP--NWISFEKVGLIDRMYDFSTDFETFYTGVPNPALSGLYASYRGETTLPQW 325
            |...|..|....:|  ..:.:|:.||:......|:|..|..|||.:....|:..::.|.|.||.|
  Fly   224 YEDPLLKLAKDVVPKEQKLPYEEFGLLYGKNGTSSDRVTVNTGVDDIRRYGIIDNFNGRTHLPHW 288

  Fly   326 DGDHCSNIEFASDGTKFKSFIQPNETVKFFRKSMCRPINLYRVGNEKTYGSLKGYNYVFEDNAFD 390
            ..|.|:.:. .:||:.|...|..:..:..:.|.:||.:.|.......|...:.||.:...:..|.
  Fly   289 TTDACNTLA-GTDGSIFPPHIDHDRILHVYDKDLCRLLPLVFEKEVMTSNEVPGYRFTPPEWVFA 352

  Fly   391 NGATNEANKCFCRKG--DCQPVGLIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPD-PDKH 452
            :..::..|.|||..|  .|.|.||.:|:.|.|..||.||||||...|..|:..|.||||. .:||
  Fly   353 DVDSHPDNMCFCPAGKPSCSPNGLFNVSLCQYDSPIMLSFPHFYLADESLRTQVEGISPPMKEKH 417

  Fly   453 SSTFVIQPESGLPLSLSVKVQINM------HFKDLSNFPVVSVFNHLTVPMLWFEIMMSKLPDSL 511
            ...|.:||:.|..|.:..::|||:      ..|.::|||.: :|     |:||||..:..|||.:
  Fly   418 QFFFDVQPKMGTTLRVRARIQINLAVSQVFDIKQVANFPDI-IF-----PILWFEEGIDNLPDEV 476

  Fly   512 DSRFNFYLNILPLVNPLGFWSGILLGISLLGYAITKATLHMSTFSRRAANITDVKYVRANLIQNI 576
            .....|...:.|.:.     ..:::|:..||..:    |.:|||.               ||:|
  Fly   477 TDLMRFAEQVPPKIR-----VALIVGLCALGVIL----LLLSTFC---------------LIRN- 516

  Fly   577 AGEAANHAYSPCDIKLLDDISVVRHPVNKQTVQDS 611
                 :|..|...::..:.::..:..:||:..:|:
  Fly   517 -----SHRQSTLHLEGSNYLATAQVDMNKKQNKDN 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	140/476 (29%)
emp	NP_726504.2	CD36	58..511	CDD:279474	139/471 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450691
Domainoid	1	1.000	168	1.000	Domainoid score	I2304
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I2746
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900