DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG40006 and pes

DIOPT Version :9

Sequence 1:	NP_001036401.1	Gene:	CG40006 / 3355123	FlyBaseID:	FBgn0058006	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_001137808.1	Gene:	pes / 34087	FlyBaseID:	FBgn0031969	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	124/551 - (22%)
Similarity:	235/551 - (42%)	Gaps:	72/551 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RNRVPTRLFILLVIGFLAIITSTLI--KVLEPYDLIFKWKLIMTEGGEIFNLWAQPPVDLYIKIY 146
            |.|...||.|:| :|...|.:...:  ..::.:..:...::.::.....|..|...|:.|...||
  Fly     4 RTRHCARLGIVL-LGICCIASGIYLFRNWIDMFTRMRGQEMALSPNSRSFEGWKVSPLPLDFDIY 67

  Fly   147 LFNITNANAFLAG-REQLRVEQVGPYVYKEIMTHENVTFNSNNTMSSTPSHPLVW--QEEMSGNC 208
            |||.||.:.|..| .::...||:|||.::|.....::.::::|  :|...|...|  .:....|.
  Fly    68 LFNWTNPDDFYVGSNKKPHFEQLGPYRFREKPDKVDIEWHNHN--ASVSFHKKSWFYFDAAGSNG 130

  Fly   209 REDDEVVMLNIAMLAISHLTANQPFL-------VRMALKTLLLSTKSEPIVRTTAKEFMFGYPSA 266
            ...|:|..:|    :::|..|.:..:       |.:|.|   |..:...|.:|..:....||...
  Fly   131 SLWDKVTTVN----SVAHSAARRAAVDWFARTGVNIANK---LYRQGVTITKTVDEMLFKGYEHP 188

  Fly   267 LATLGNTFLPNWISFEKVGLIDRMYDF----STDFE---TFYTGVPNPALSGLYASYRGETTLPQ 324
            ..::|....|..:.::::|     |.:    |::|:   ..:||..:.|..|...::...|....
  Fly   189 FISVGKLLRPQDVPYKRIG-----YHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGA 248

  Fly   325 WDGDHCSNIEFASDGTKFKSFIQPNETVKFFRKSMCRPINLYRVGNEKTYGSLKGYNYVFEDNAF 389
            ::|. |..:. .|.|..|...:...:||..:...|||.|.|..|.....:| :..|.:....:|.
  Fly   249 FEGT-CGQVH-GSMGEFFPPNLGTKDTVYMYMPKMCRAIPLDYVETVTVHG-VTAYKFSGTRHAV 310

  Fly   390 DNGATNEANKCFCRKGDCQPVGLIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSS 454
            |||......:|:|..|.|.|.|:|::..|.:...:.:|||||...|....:.:.|:.|:.:||..
  Fly   311 DNGTLYPDTRCYCVGGKCMPSGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEF 375

  Fly   455 TFVIQPESGLPLSLSVKVQINMHFKDLSNFPVVSVFNH---LTVPMLWFEIMMSKLPDSLDSRFN 516
            ...::|.:|:|:.:....|.|.:.:.:   |.::::.:   :.:||:|.|..: ::.:.:.:.
  Fly   376 FMALEPNAGVPMDVGGGFQANYYMEPI---PGITLYENVPTVMIPMMWCEERV-RVSEEIAAD-- 434

  Fly   517 FYLNILPLVNPLGFWSGILLGISLLGYAI------TKATLHMSTFSRRA------------ANIT 563
              :.::||:..||   .|:.||.|.|..|      |:...|......:|            .|.:
  Fly   435 --IALVPLIVLLG---QIVTGILLAGGLICTCWYPTRQVTHFCHSDPKAKASVLRPLNAFGVNSS 494

  Fly   564 DVKYVRANLIQNIAGEAANHAYSPCDIKLLD 594
            ......|.|.:|....:.|....   ::|||
  Fly   495 AATAPVAQLFRNNISSSGNERVG---VRLLD 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	109/475 (23%)
pes	NP_001137808.1	CD36	14..463	CDD:279474	108/477 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450696
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850