Protein Alignment CG40006 and Cd36

DIOPT Version :10

• Sequence 1: NP_001036401.1
• Gene: CG40006 / 3355123
• FlyBaseID: FBgn0058006
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_113749.2
• Gene: Cd36 / 29184
• RGDID: 2301
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 469
• Identity: 114/469 - (24%)
• Similarity: 221/469 - (47%)
• Gaps: 51/469 - (10%)

  Fly    96 VIG-FLAIITSTLIKVLEPYDLI----FKWKLIMTEGGEIFNLWAQPPVDLYIKIYLFNITNANA 155
            ||| .||:....|:.|   .||:    .|.::::.||...|..|.:....:|.:.::|::.|...
  Rat    14 VIGAVLAVFGGILMPV---GDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEE 75

  Fly   156 FLAGREQLRVEQVGPYVYK-EIMTHENVTFN-SNNTMSSTPSHPLVWQEEMSGNCREDDEVVMLN 218
            ......:::|:|.|||.|: ..:..||:|.: .::|:|....:..:::..:|.. .|:|...:||
  Rat    76 VAKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVG-TENDNFTVLN 139

  Fly   219 IAMLAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFGY--------PSALATLGNTFL 275
            :|:.|..|:..|.  .|:..|.:|:..:||......:.||.::||        |..::|....|.
  Rat   140 LAVAAAPHIYTNS--FVQGVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFY 202

  Fly   276 P-NWISFEKVGLIDRMYDFSTDFETFYTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDG 339
            | |       ..:|.:|       ..:.|..|.:...:..:|:|:..|..|: .:|..|. .:|.
  Rat   203 PYN-------NTVDGVY-------KVFNGKDNISKVAIIDTYKGKRNLSYWE-SYCDMIN-GTDA 251

  Fly   340 TKFKSFIQPNETVKFFRKSMCRPINLYRV-GNEKTYGSLKGYNYVFEDNAFDNGATNEANKCFCR 403
            ..|..|::.:.|::||...:||  ::|.| |:|.....:..|.:|...|||.:...|..|.|||.
  Rat   252 ASFPPFVEKSRTLRFFSSDICR--SIYAVFGSEVNLKGIPVYRFVLPANAFASPLQNPDNHCFCT 314

  Fly   404 K----GDCQPVGLIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGL 464
            :    .:|...|::|:..|..|.|:.:|.|||::....:.:.:.|::|:.|:|.:...::|.:|.
  Rat   315 EKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLNPNEDEHRTYLDVEPITGF 379

  Fly   465 PLSLSVKVQINMHFKDLSNFPVV-SVFNHLTVPMLWFEIMMSKLPDSLDSRFNFYLN-ILPLVNP 527
            .|..:.::|:|:..|.......: ::.....||:||    :::.....|.:...:.| :...:..
  Rat   380 TLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILW----LNETGTIGDEKAEMFRNQVTGKIKL 440

  Fly   528 LGFWSGILLGISLL 541
            ||....:|||:.::
  Rat   441 LGLVEMVLLGVGVV 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	96..545	CDD:460076	114/469 (24%)
Cd36	NP_113749.2	CD36	14..463	CDD:460076	114/469 (24%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000250	93..120		6/26 (23%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000250|UniProtKB:P16671	460..472