DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40006 and Scarb1

DIOPT Version :9

Sequence 1:	NP_001036401.1	Gene:	CG40006 / 3355123	FlyBaseID:	FBgn0058006	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_001192012.1	Gene:	Scarb1 / 20778	MGIID:	893578	Length:	520	Species:	Mus musculus

Alignment Length:	519	Identity:	140/519 - (26%)
Similarity:	248/519 - (47%)	Gaps:	35/519 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 FILLVIGFLAIITSTL--IKVLEPYDLIFK--WKLIMTEGGEI-FNLWAQPPVDLYIKIYLFNIT 151
            ::.|.:|.|.::.:.|  :.:|....||.:  .|.:..:...: |.:|.:.||..|:.:|.|.:.
Mouse     9 WVALGLGALGLLFAALGVVMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVV 73

  Fly   152 NANAFLAGREQLRVEQVGPYVYKEIMTHENVTFNSNNTMSSTPSHPLVWQEEMSGNCREDDEVVM 216
            |.|..|.|::.: |.:.|||||:|.....|:|||.|:|:|...:..|.:|.:.| :..|.|.:|:
Mouse    74 NPNEVLNGQKPV-VRERGPYVYREFRQKVNITFNDNDTVSFVENRSLHFQPDKS-HGSESDYIVL 136

  Fly   217 LNIAMLAISHLTANQPFLVRMALKTLLLSTKSEPIVRTTAKEFMFGYPSALATLGNTFLPNWISF 281
            .||.:|..|.|..::|..:::.:...|::......:..|..|.::||........||:||:.:..
Mouse   137 PNILVLGGSILMESKPVSLKLMMTLALVTMGQRAFMNRTVGEILWGYDDPFVHFLNTYLPDMLPI 201

  Fly   282 E-KVGLIDRMYDFSTDFETFYTGVPNPALSGLYASYRGETTLPQWDGDHCSNIEFASDGTKFKSF 345
            : |.||...|.:.::...|.:|||.|.:...|...:.|.:.:..|..:.|:.|. .:.|..:..|
Mouse   202 KGKFGLFVGMNNSNSGVFTVFTGVQNFSRIHLVDKWNGLSKIDYWHSEQCNMIN-GTSGQMWAPF 265

  Fly   346 IQPNETVKFFRKSMCRPINLYRVGNEKTYGSLKGYNYVFEDNAFDNGATNEANKCFCRKGDCQPV 410
            :.|..:::||....||.:.| .....:.:..:..|.:...|..|.||:....|:.||   .|:..
Mouse   266 MTPESSLEFFSPEACRSMKL-TYNESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFC---PCRES 326

  Fly   411 GLIDVTDCYYGFPISLSFPHFMNGDVGLQQNVTGISPDPDKHSSTFVIQPESGLPLSLSVKVQIN 475
            |:.:|:.|.:|.|:.||.|||.|.|..|.:.|.|::|:|.:||....|.|.:|:|::.|||:|::
Mouse   327 GIQNVSTCRFGAPLFLSHPHFYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLS 391

  Fly   476 MHFKDLSNFPVVSVFNHLTVPMLWFEI--MMSKLPDSLDSRFNFYLNILPLVNPLGFWSGILLGI 538
            ::.|.:...........:.:|:||||.  .|...|.|     .||..::.:...|.:...:|||:
Mouse   392 LYIKSVKGIGQTGKIEPVVLPLLWFEQSGAMGGKPLS-----TFYTQLVLMPQVLHYAQYVLLGL 451

  Fly   539 SLLGYAITKATLHMSTFSRRAANITDVKYVRANLIQNIAGEAANHAYSPCDIKLLDDISVVRHP 602
            ..|...:.......|..|||..:.:|...|.|:|               |.::|...:..:.||
Mouse   452 GGLLLLVPIICQLRSQVSRRGGHASDSARVSADL---------------CFLQLALVLPPLSHP 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40006	NP_001036401.1	CD36	91..545	CDD:279474	128/460 (28%)
Scarb1	NP_001192012.1	CD36	26..447	CDD:279474	120/432 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.876977	Normalized mean entropy	S6407
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.800