DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and AT4G19750

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_193710.2	Gene:	AT4G19750 / 827719	AraportID:	AT4G19750	Length:	362	Species:	Arabidopsis thaliana

Alignment Length:	390	Identity:	113/390 - (28%)
Similarity:	158/390 - (40%)	Gaps:	57/390 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1895 TSVITEPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDS 1959
            |..:....|:..||          |....:..|...:||:...|||...||.:||     .||:.
plant     5 TQFLRTNSIVKASY----------WVVKPENDFPAGNIDSTRFTHLFCAFADVDS-----STHEV 54

  Fly  1960 WTDIDN----RFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFVASVISFLEQH 2020
            .....|    ..:...|:.|...::.:|:||| .|:..:..|.:..||::|:.|:.|.|....:.
plant    55 TISAANSCQVSSFTHTVKDKNTDVQTLLSIGG-KDADKAVLASMASNSKNRKAFIDSSIDIARKK 118

  Fly  2021 GFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENG-------LILSAAVSPSKMV 2078
            .|.|||||||:|         .|..|...|..||||...|..|..       |:|:|||..|...
plant   119 DFYGLDLAWEYP---------SNDVEMANFGKLVKEWRAAVVEESDRTNQLPLLLTAAVYYSPDY 174

  Fly  2079 IDAGYNVFELSPYFDWVAVMTYDFHG-HWDMRTGQIAPLFH------RGGDENLYLNGNFSIHYW 2136
            ....|.|..::...|:|.:|.|||:| .|...||..|.||.      |.||..|        ..|
plant   175 YGEEYPVQAIADNLDFVNIMAYDFYGPGWSPVTGPPAALFDPSNPAGRSGDSGL--------SKW 231

  Fly  2137 LERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDW 2201
            ||..:|..|.|:|....|..:||.|......:..|     .|....:||.:.|.:|...:: |:.
plant   232 LEAKLPAKKAVLGFSYCGWAWTLEDAENNGYDAAT-----DGAAISSDGSITYAKIRNYII-DNG 290

  Fly  2202 KVVRDEEGIFGSYAYSGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRGLCGCGKHPL 2266
            .....:..:.|.|.|.|..||.|||..:|..|.::.|...|.|...|.:..|...||...|...|
plant   291 AATFHDPAVIGFYCYVGTTWIGYDDNQSIVSKVRYAKLKGLLGYFSWHVGADYNCGLSRAGSFSL 355

Fly 2267 2266
plant 356 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	104/361 (29%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	109/375 (29%)
AT4G19750	NP_193710.2	GH18_plant_chitinase_class_V	11..348	CDD:119358	109/375 (29%)
AT4G19750	NP_193710.2	Glyco_18	14..342	CDD:214753	106/366 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920