DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and Muc26B

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_652552.1	Gene:	Muc26B / 50424	FlyBaseID:	FBgn0040950	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	70/281 - (24%)
Similarity:	100/281 - (35%)	Gaps:	76/281 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   593 PPTQPNCKRPTLLATPVPPQMTTISSDGSGGLGQNHDHTTSLPSGQISSSPVSTTI---TSTFPW 654
            |.|...| .||...|..|...||.:...:         ||..|:...:.:|.:||.   |:|...
  Fly   239 PTTTTTC-APTTTTTCAPTTTTTCAPTTT---------TTCAPTTTTTCAPTTTTTCAPTTTTTC 293

  Fly   655 WSSTTKRPREPTKTTAQPTHTTILIP---AGINPVVQPSNCKSGEFFADSNNCNAYYHCFFAGEL 716
            ..:||......|.||..||.||...|   ....|.:..:.|..    |.:..|........|...
  Fly   294 APTTTTTCAPTTTTTCAPTTTTTCAPTTTTTCTPGITTTTCTP----ATTTTCVPETTTSCASST 354

  Fly   717 QQQFC--PSGLHWNNEAKGCDWPSSAQCSLKLDQHLSTSYPNPIQTSKKPETTLKPNKKPS-EIS 778
            ....|  .||:..:::|:    |||.:.                    :|...::|..:|: ||.
  Fly   355 TTTECGPVSGVSGSSKAR----PSSVKV--------------------RPARPVRPAVRPALEID 395

  Fly   779 THHQVNSTSSRPQYMRPTILECTEGDY--YPHRN------------CRKYYIC-VNKALVPSECG 828
                        :...|...|.|...|  |..||            |..|||| ..|.|:.| |
  Fly   396 ------------ELSAPKAQELTMSTYTKYVCRNKPDGFMLASLKSCSDYYICRYGKPLLVS-C- 446

  Fly   829 GDLHWDGIKKLCDWPENVQCV 849
            ||.:::.:|.:||.|||.:||
  Fly   447 GDKYFNALKGICDLPENTRCV 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696	7/41 (17%)
		CBM_14	801..848	CDD:279884	22/61 (36%)
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Muc26B	NP_652552.1	CBM_14	43..86	CDD:279884
Muc26B	NP_652552.1	CBM_14	415..463	CDD:279884	17/49 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900