DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht10 and chit1

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_001005792.1	Gene:	chit1 / 448265	XenbaseID:	XB-GENE-5801457	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	446	Identity:	163/446 - (36%)
Similarity:	248/446 - (55%)	Gaps:	45/446 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   965 YKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTRVT 1029
            ||::||||||:.||....::.|.:|:.:||||:||.||.::.:::   ....|.|  :..|.:..
Frog    22 YKLVCYFTNWSQYRPEPAKYMPGNIDPKLCTHLIYAFATMNSNKI---APYEWND--DVLYKQYN 81

  Fly  1030 SLKSK--GIKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPVCW 1092
            :||.:  .:...||:||||... .|::.:|.|...|..|:...:|::..|||.|:|||:|||
Frog    82 ALKQQNPNLVTLLAIGGWNFGT-QKFTEMVSSAGNRKIFIDSVIEYLRLYGFNGIDLDFEYP--- 142

  Fly  1093 QTECNKGS-TEEKDGFTAWVQELSEAFRPRG-------LMLSTAVSPSRKIIDAGYDIPQLSRYF 1149
               .::|| .|:|..||...||:.:||....       |:::.|||..:..|||||:|.::.:..
Frog   143 ---GSRGSPPEDKHRFTILTQEMLKAFEDEAAATNQSRLLMTAAVSAGKGTIDAGYEIAEIGKTL 204

  Fly  1150 DWIAVMTYDFHGHWDKKTGHVAPLYHHPDD--DFEYFNVNYSINYWMEKGAPSQKLVMGIPLYGQ 1212
            |:|:||||||||.||..:||.:||.....|  ||:|||:.|::|||.:.|.|:|||::|.|.||:
Frog   205 DFISVMTYDFHGGWDPVSGHNSPLCKGSKDTGDFQYFNIRYAMNYWKDNGVPAQKLLIGFPTYGR 269

  Fly  1213 SFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQVVHDEFGRMGPYAYKGTQ 1277
            :|...|.::..:.......|.||::||.|||.||||||..::......:.|:   ..|||.||.:
Frog   270 TFRNPNPSNCDVGIPVSGAGSAGQYTREAGFWAYYEICTWLSGTTINWIADQ---KVPYACKGNE 331

  Fly  1278 WVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVHPLLTEIHNVLKDPPSLMEIP 1341
            ||.:|:.|....|...::.....|.||||:|||||... |..|.:||::.:.::|:.  |:.:.|
Frog   332 WVGFDNQDSYECKVKFLKESGFAGAMVWAIDLDDFSGTFCNQGKYPLISHLKSLLEG--SVTKCP 394

  Fly  1342 G-PIETTPTEYPGMEEEIHESNGEGPEVQ----PIEAVMQTCENEGEEHEGILDPN 1392
            | |.:..|||.|.     ..::||....|    |.|....| ...|:|    :|||
Frog   395 GNPCDIVPTEPPS-----PTTSGETTTSQAKPTPGETTTST-TTSGDE----VDPN 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	134/355 (38%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	141/376 (38%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chit1	NP_001005792.1	GH18_chitolectin_chitotriosidase	24..386	CDD:119351	141/376 (38%)
chit1	NP_001005792.1	CBM_14	442..491	CDD:366726
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9484
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920