DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chia.1

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	398	Identity:	146/398 - (36%)
Similarity:	224/398 - (56%)	Gaps:	30/398 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTR 1027
            |..|::||.|||:.||.|.|:|.|::|:..|||||:|..|.:.|...:  |...|.||:  .|..
Zfish    20 SSTKLVCYMTNWSQYRPGNGKFLPENIDPFLCTHVVYALATISYDNQI--TTIEWNDVD--LYKS 80

  Fly  1028 VTSLK--SKGIKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPV 1090
            :..||  :..:|..|::||..:.. ..|..:|.:|..|..|:|:||.|:..:.|:|:|:||:||
Zfish    81 MNELKKVNPALKTQLSVGGLVNGV-SPYINMVATPENRKAFIRNALLFLRLHEFDGMDIDWQYP- 143

  Fly  1091 CWQTECNKGSTEEKDGFTAWVQELSEAFRPRG-------LMLSTAVSPSRKIIDAGYDIPQLSRY 1148
                ..|....::|...|.:::|:.:|.....       |:||..||..:..|:..|:..:::..
Zfish   144 ----GHNGSPPQDKQRLTTFIKEMRDAIEQEAIDTKKTPLLLSIKVSAIKTTIENAYEAKEVASL 204

  Fly  1149 FDWIAVMTYDFHGHWDKKTGHVAPLYHHPDD--DFEYFNVNYSINYWMEKGAPSQKLVMGIPLYG 1211
            .|::.:|:||:|||||..|||.:||:....|  ...:.|:|.|:.:|:..|||:.:|::|:|.||
Zfish   205 VDFVTIMSYDYHGHWDPITGHNSPLFRSSFDTGSIVHHNINSSLEFWLGSGAPADRLLLGLPTYG 269

  Fly  1212 QSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQVVH--DEFGRMGPYAYK 1274
            ::|.| :|:.:||.|.|..|.:||.:||.|||.:|||||.   .:....:|  ||  :|.|||.:
Zfish   270 RTFML-STSQTGLGAPANGPADAGPYTREAGFWSYYEICP---MESSVPIHWIDE--QMVPYAVQ 328

  Fly  1275 GTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVHPLLTEIHNVLKDPPSLM 1338
            |..||.:|:.:.:..|...:.||||||..||.||.|||..| |.||.:||:..:.|.|..||...
Zfish   329 GRAWVGFDNQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPLVNHLRNSLGFPPKPT 393

  Fly  1339 EIPGPIET 1346
            ..|.|..|
Zfish   394 TTPRPTTT 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	129/356 (36%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	138/377 (37%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	129/356 (36%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	138/377 (37%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6443
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850