DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and Idgf5

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster

Alignment Length:	437	Identity:	120/437 - (27%)
Similarity:	197/437 - (45%)	Gaps:	73/437 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 QQSYGALGLANRNDLKMTKKVLCYMSNWAFYRSGEAHFVPEQIDPNL--CSAIIYSFASLDPDHL 263
            |.:|..:|           |::|:....:|.|.|.|.....:::|.|  |:.::|.:|.:|....
  Fly    22 QSTYAEVG-----------KLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTY 75

  Fly   264 TIREFDSWVDLDNQYYRRVTSL-----GVPVLIALGGWTD------SSGSKYSRLVSDNLKRRVF 317
            .|:..|..:..|.|:||.:|:|     .|..|:::||..|      :...||.||:..:..|:.|
  Fly    76 KIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSF 140

  Fly   318 ISSVSSFLLRHGFSGLHLDWNYPK------------------CWQSDCSRGPVTD--RPNLTKLL 362
            .:||.:.|..:||.|:.|.|.:||                  .|.|..|....::  |.....||
  Fly   141 QASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLL 205

  Fly   363 RELRTEFQSVDPKFQLGVAISGYKEIIKEAY-DFPALSDIVDYMTVMTYDYH-GAWEQKTGHV-S 424
            .||:::.:...   || :.:|....:..|.: |.|.:...||::.:.|||:. ...:.|...: :
  Fly   206 EELQSDLRRGG---QL-LTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPT 266

  Fly   425 PLYGLSSDTYPQYNTNYTMQLLLKMGAR--REKLVLSIPFYGQSFTLATAHQILAGPGV-AASGP 486
            |||.: .|..|.:|..|.:|..:...:.  ..||.:.:..||:::.:.....|...|.: ||:|.
  Fly   267 PLYAM-YDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGA 330

  Fly   487 GDAGELTKQPGMLAYYEICQRLTKFNWISDRNLNVI---------FGPFA--MLNDQ-----WVG 535
            ...|..|..||:|::.|||..|.:  ...||.:..:         ||.:|  ..:||     |||
  Fly   331 APPGRQTVTPGLLSWPEICDLLQQ--QPQDREVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVG 393

  Fly   536 YEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAI 582
            ||||.:|..||.:.......|||...:.:||||..|..|.:|:||:|
  Fly   394 YEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753	107/399 (27%)
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351	116/417 (28%)
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	117/418 (28%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	107/399 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463781
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840