DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and Idgf1

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	121/425 - (28%)
Similarity:	203/425 - (47%)	Gaps:	78/425 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1910 VVCYFTSWAWYRSSQGKFVPEDIDANL--CTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYERVV 1972
            ::||:.|.::.|....|....::|..|  ||||:||:|.|  ||.|::......|:|..:|:.:.
  Fly    24 LICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGL--KSGTLELFSLNVDLDMFYYKDIT 86

  Fly  1973 EYKQR--GLRVMLAIGGWND---SLGSKYARLV-LNSQSRRRFVASVISFLEQHGFEGLDLAWEF 2031
            ..:|:  .|:::|::||..|   :..:||..|: .|..:::.|:.|.:..|:::||:|||||::.
  Fly    87 ALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQL 151

  Fly  2032 PVCWQVNCNRGNPTE-----------------------------KDGFVALVKELSEAFKENGLI 2067
            |        |..|.:                             |..|..||..:..||:...|:
  Fly   152 P--------RNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKNAFRSANLM 208

  Fly  2068 LSAAVSPSKMVIDAGY-NVFELSPYFDWVAVMTYDFHGHWDMRTGQ----IAPLFHRGGDENL-Y 2126
            ||..|.|:  |....| :|.:|.|.||::.:..:||  ...:|..:    .||:|.:.....| :
  Fly   209 LSLTVLPN--VNSTWYFDVPKLHPQFDYINLAAFDF--LTPLRNPEEADFTAPIFFQDEQNRLPH 269

  Fly  2127 LNGNFSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRS---LNDKTVGPGKAG-TFTRADGFL 2187
            ||..|.|:|||:...|..||.:|:..||:.:.|:..:..|   :..:|.|....| ....|:|.|
  Fly   270 LNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHETCGVAPGGIQIQSAEGLL 334

  Fly  2188 AYYEICEKVVND----------DWKVVRDEEGIFGSYAY-----SGN--QWISYDDVTTIRRKSQ 2235
            ::.|||.|:..:          ..:.|.|....:|:||.     :|:  .|:|:||......|:.
  Fly   335 SWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIKAV 399

  Fly  2236 FIKSLQLGGGMIWALDLDDFRGLCGCGKHPLLRTL 2270
            :.|...|||..::.|..|||||||...|:|:||::
  Fly   400 YAKGKGLGGIALFDLSYDDFRGLCTGQKYPILRSI 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	110/406 (27%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	121/425 (28%)
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	121/425 (28%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	110/406 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840