DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and Cht11

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_572361.1	Gene:	Cht11 / 31630	FlyBaseID:	FBgn0029913	Length:	432	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	111/390 - (28%)
Similarity:	197/390 - (50%)	Gaps:	52/390 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1410 KIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADL---DNKFYER 1471
            :::||:.:     .|.......|:..||||||..|.|.|  ||.||...|:...:   |.:
  Fly    68 RLVCYYAS-----DGTHNLSLLDVPGDLCTHINIGPATL--DNATIVLPDTLRQVLQNDTR---- 121

  Fly  1472 IVAYRKKGAKVTVA--IGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEY-NFDGLDLDWEYP 1533
              ::|....:|.:.  |||  ..:|..::.:|.|...|..|:|::.:.:..| :.||:|||||:|
  Fly   122 --SFRAAHPQVHLLLWIGG--ADSGRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFP 182

  Fly  1534 VCWQVDCKKGTAEEKIGFSALVRELFYAFQPR---GLILSAAVSPNKKVIDAGYEVAELSHYFSW 1595
            ..:.        .|::..|.|:.|:...::..   ..|||.||:..:.:....|::.|::.|..:
  Fly   183 SAYD--------RERMHLSQLLYEIRTEWRREKRTNDILSLAVAAPEGIAFYAYDIREINLYADY 239

  Fly  1596 ISVMAYDYHGQWDKK--TGHVAPMYSHPEG---TANFNANFSMNYWISMGADRRKLVMGIPLYGQ 1655
            :::|:||:|...:..  ||..||:|:..:.   .|.||.|:::.:|:..|.:.::||:|:|.||.
  Fly   240 VNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGH 304

  Fly  1656 SFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKI-RHHRWNVVRDTKGRIGPFAYHGD 1719
            ||:|.....|::.||..|.|:.|:.    ||....|.|..: :..:.|:..|.:. ..|:.....
  Fly   305 SFTLVNPLNHRIGAPASGYGKCGQL----GFTTLTETCECVTKFFKPNLSYDAES-CSPYLSALQ 364

  Fly  1720 QWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNVC---------ECESYPLLKAINRVLR 1775
            :|:|:::...|..|:.|:|::.|||.|:::|:.||.||.|         |...:||.:||..:||
  Fly   365 EWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAIKDILR 429

Fly 1776 1775
Fly 430 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	99/357 (28%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	109/386 (28%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Cht11	NP_572361.1	Glyco_18	68..398	CDD:214753	99/357 (28%)
Cht11	NP_572361.1	GH18_chitinase-like	69..428	CDD:299167	109/386 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920