DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and Chi3l3

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	XP_008759605.2	Gene:	Chi3l3 / 295351	RGDID:	1308790	Length:	401	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	139/389 - (35%)
Similarity:	212/389 - (54%)	Gaps:	41/389 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTR 1027
            |.|:::||:|:||..|..:|.|...:|:..||||:||.||.:..:|::..:.....|     |..
  Rat    20 SSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIYAFAGMRNNEIINTSEQDLID-----YEA 79

  Fly  1028 VTSLKSKG--IKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPV 1090
            :..||.:.  :|..||:|||..... .:|.:|.:|..|..|::..::|:.:|.|:||:|||:||
  Rat    80 INYLKDRNTELKTLLAIGGWKFGSA-PFSAMVSTPQNRQTFIKSVIKFLRQYKFDGLNLDWQYP- 142

  Fly  1091 CWQTECNKGS-TEEKDGFTAWVQELSEAFR--------PRGLMLSTAVSPSRKIIDAGYDIPQLS 1146
                 .::|| .::|..|:..|||:.:||.        || |:|:..|:.....|.:||.||:||
  Rat   143 -----GSRGSPPKDKHLFSVLVQEMRKAFEKESTEQEIPR-LLLTATVAGVIDTIQSGYKIPELS 201

  Fly  1147 RYFDWIAVMTYDFHGHWDKKTGHVAPLYHHPDDD--FEYFNVNYSINYWMEKGAPSQKLVMGIPL 1209
            :..|:..||||:.|...:..|...:|||..|.|.  :.|.||:..|:||.:.||..:||::|.|.
  Rat   202 QSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSDTGIYAYLNVDAIISYWKDNGAAREKLIVGFPA 266

  Fly  1210 YGQSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNR------QGWQVVHDEFGRM 1268
            ||.:|.|.:.:::|:||...:.|..|:||..||..||||||..:|.      .|.|.|
  Rat   267 YGHNFILSDPSNTGINAPIVSTGPPGKFTGEAGLWAYYEICTFLNDGATDLWDGPQEV------- 324

  Fly  1269 GPYAYKGTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVHPLLTEIHNVL 1331
             |||.:|..||.||:....:.|:..::..||||.|||.||:|||... |..|..||.:.:.:.|
  Rat   325 -PYAVQGNVWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQGRFPLTSTLKHYL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	129/362 (36%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	136/383 (36%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Chi3l3	XP_008759605.2	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	136/383 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020