DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cht10 and Chil5

DIOPT Version :9

Sequence 1:NP_001036422.1 Gene:Cht10 / 3355116 FlyBaseID:FBgn0250907 Length:2286 Species:Drosophila melanogaster
Sequence 2:NP_001074285.1 Gene:Chil5 / 229687 MGIID:2676649 Length:431 Species:Mus musculus


Alignment Length:386 Identity:144/386 - (37%)
Similarity:220/386 - (56%) Gaps:35/386 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTR 1027
            |.|:::||:.|.|..|..:|.|.|.||:..||||:||.||.:..:::.:|:.:...|     |..
Mouse    20 SAYQLMCYYNNVAQNRPKLGSFNPADIDPCLCTHLIYAFAGMQNNKVTMRSMNDLTD-----YQA 79

  Fly  1028 VTSLKSKGI--KVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPV 1090
            :.:|||:.:  |..||:|| .|.....:|.:|.:|..:..|:..|::|:.:|||:||:|||::| 
Mouse    80 LNTLKSRNVQLKTLLAIGG-RDFGPAPFSAMVSTPHNQQTFINSAIKFLRQYGFDGLNLDWQFP- 142

  Fly  1091 CWQTECNKGS-TEEKDGFTAWVQELSEAFR--------PRGLMLSTAVSPSRKIIDAGYDIPQLS 1146
                 .::|| :.:|..||..||::.|||.        || ||::..|:.....|.:||:|||||
Mouse   143 -----GSRGSPSRDKHLFTVLVQKIREAFELEAIENKSPR-LMVTATVAGVISTIQSGYEIPQLS 201

  Fly  1147 RYFDWIAVMTYDFHGHWDKKTGHVAPLYHHPDDD--FEYFNVNYSINYWMEKGAPSQKLVMGIPL 1209
            .:.|:|.||||:.||..|..||..:|||...:|.  ....||:|.:.||.|.||..:||::|.|.
Mouse   202 HFLDYIQVMTYNLHGSQDGYTGENSPLYKSLNDTGINTLLNVDYIMTYWNENGAAPEKLIVGFPA 266

  Fly  1210 YGQSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVN---RQGWQVVHDEFGRMGPY 1271
            |||:|||.:.:::|::|...:.|..|.:|..:|..||||||..:|   .:.|....:.     ||
Mouse   267 YGQTFTLSDPSNNGISAPTASAGTLGPYTEESGTWAYYEICSFLNDGATEAWDSAQEV-----PY 326

  Fly  1272 AYKGTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVHPLLTEIHNVL 1331
            ||:|.:||.||:....|.|:..::...|||.|:|.||:|||... |..|..||.:.:.|.|
Mouse   327 AYQGNKWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCNQGQFPLTSTLKNAL 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cht10NP_001036422.1 Glyco_18 220..565 CDD:214753
GH18_chitolectin_chitotriosidase 221..586 CDD:119351
ChtBD2 697..737 CDD:214696
CBM_14 801..848 CDD:279884
CBM_14 875..918 CDD:279884
Glyco_18 966..1310 CDD:214753 133/359 (37%)
GH18_chitolectin_chitotriosidase 967..1331 CDD:119351 141/380 (37%)
Glyco_18 1410..1753 CDD:214753
GH18_chitolectin_chitotriosidase 1411..1774 CDD:119351
ChtBD2 1834..1871 CDD:214696
Glyco_18 1909..2253 CDD:214753
GH18_chitolectin_chitotriosidase 1910..2274 CDD:119351
Chil5NP_001074285.1 GH18_chitolectin_chitotriosidase 24..387 CDD:119351 141/380 (37%)
Glyco_18 26..365 CDD:214753 133/356 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264489at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8820
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11177
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
55.020

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